Cell membrane-derived nanoparticles for active targeting to tumor cells

Nanotechnology has enabled many improvements in cancer therapy, in terms of increased efficacy in selective drug delivery and limited systemic toxicity. Within this context, cell membrane-derived nanoparticles represent an alternative to extracellular vesicles allowing to retain the complexity and versatility of the cell membrane, and overcoming the limits of vesicles isolation and of traditional surface modification approach. The purpose of this work is to develop a safe cell-derived nanosystem for drug delivery to target parent malignant tumor cells.