THE ROLE OF ANTIBIOTIC DOSING SYSTEM IN PEDIATRICS INFECTIOUS DISEASES: IT’S A LONG WAY TO THE TOP (if you wanna achieve PTA)

A TDM-guided anti-infective therapy especially in the most complex clinical situations and/or in presence of antibiotic resistant pathogens should be started in order to personalize therapy. The possibility of evaluating plasma concentrations of antibiotics in pediatric patients, especially in the most complex clinical conditions, can have important scientific implications and, more importantly, be reflected in daily clinical activity. With a solid TDM system the clinician could go beyond the choice of the best molecule for the single pathogen, but also adapt the administration schedule and the posology on individual patient in the individual hospitalization setting.