Organic FET-based transistor arrays for metabolic and electrophysiological measurements

My PhD project aimed at designing and validating an array of sensors capable of measuring simultaneously the electrophysiological and the metabolic activities of in vitro excitable cell cultures. In particular, these sensors are based on a peculiar kind of organic field effect transistor, called organic charge modulated field effect transistor or OCMFET, and can be easily integrated in a single substrate to measure the two parameters. This array has been tested using in vitro cardiomyocytes. In addition, an equivalent electrical model of the sensors has been created and used to help analysing the recording data.