KUMAR, MANDEEP
KUMAR, MANDEEP
100008 - Dipartimento di medicina sperimentale
In-vitro and in-vivo studies depict metabotropic glutamate receptor 5 as a potential pharmacological target to modulate disease progression in ALS
2021-01-01 Milanese, M.; Torazza, C.; Provenzano, F.; Bonifacino, T.; Ravera, S.; Balbi, M.; Frumento, G.; Kumar, M.; Cerminara, M.; Puliti, A.; Usai, C.; Bonanno, G.
In-vivo and in-vitro evidence supporting the role of mGlu5 receptor as a key regulator of glutamate downstream effects in ALS
2021-01-01 Milanese, Marco; Bonifacino, Tiziana; Torazza, Carola; Provenzano, Francesca; Kumar, Mandeep; Ravera, Silvia; Zerbo, ROBERTA ARIANNA; Frumento, Giulia; Balbi, Matilde; Nguyen T. P., Nhung; Ferrando, Sara; Viale, Maurizio; Bonanno, Giambattista
mGlu5 receptor negative allosteric modulation reduces the aberrant cellular reactivity and neurotoxicity of reactive human astrocytes differentiated from fibroblast of SOD1 and C9orf72 ALS patients
2024-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Bacchetti, Francesca; Ravera, Silvia; Musante, Ilaria; Scudieri, Paolo; Bonifacino, Tiziana; Frizzi, Benedetta; Angeli, Elena; Bazzurro, Virginia; Zara, Federico; Van Den Bosch, Ludo; Ferraiuolo, Laura; J Shaw, Pamela; Bonanno, Giambattista; Milanese, Marco
Reactive Astrocytes from patients affected by Amyotrophic Lateral Sclerosis: how mGlu5 receptor modulation affects pathological features
2024-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Ravera, Silvia; Musante, Ilaria; Bonifacino, Tiziana; Angeli, Elena; Shaw, Allan; J Shaw, Pamela; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco
Reactive phenotype and oxidative stress in i-Astrocytes from patients affected by Amyotrophic Lateral Sclerosis: how the mGluR5 negative allosteric modulator CTEP affects these pathological features
2023-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Ravera, Silvia; Musante, Ilaria; Bonifacino, Tiziana; Angeli, Elena; Shaw, Allan; Pamela, J Shaw; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco
The negative allosteric modulator CTEP ameliorates the reactive phenotype of iastrocytes from patients affected by Amyotrophic Lateral Sclerosis
2022-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Shaw, Allan; Pamela, J Shaw; Bonanno, Giambattista; Milanese, Marco
The negative allosteric modulator CTEP ameliorates the reactive phenotype of human-derived iAstrocytes differentiated from iNPCs of patients affected by Amyotrophic Lateral Sclerosis
2022-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Bonifacino, Tiziana; Shaw, Allan; Bacchetti, Francesca; Pamela, J Shaw; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco
The negative allosteric modulator CTEP ameliorates the reactive phenotype of iastrocytes from patients affected by Amyotrophic Lateral Sclerosis
2022-01-01 Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Allan, Shaw; Pamela, J Shaw; Laura, Ferraiuolo; Bonanno, Giambattista; Milanese, Marco
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| In-vitro and in-vivo studies depict metabotropic glutamate receptor 5 as a potential pharmacological target to modulate disease progression in ALS | 1-gen-2021 | Milanese, M.; Torazza, C.; Provenzano, F.; Bonifacino, T.; Ravera, S.; Balbi, M.; Frumento, G.; Kumar, M.; Cerminara, M.; Puliti, A.; Usai, C.; Bonanno, G. | |
| In-vivo and in-vitro evidence supporting the role of mGlu5 receptor as a key regulator of glutamate downstream effects in ALS | 1-gen-2021 | Milanese, Marco; Bonifacino, Tiziana; Torazza, Carola; Provenzano, Francesca; Kumar, Mandeep; Ravera, Silvia; Zerbo, ROBERTA ARIANNA; Frumento, Giulia; Balbi, Matilde; Nguyen T. P., Nhung; Ferrando, Sara; Viale, Maurizio; Bonanno, Giambattista | |
| mGlu5 receptor negative allosteric modulation reduces the aberrant cellular reactivity and neurotoxicity of reactive human astrocytes differentiated from fibroblast of SOD1 and C9orf72 ALS patients | 1-gen-2024 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Bacchetti, Francesca; Ravera, Silvia; Musante, Ilaria; Scudieri, Paolo; Bonifacino, Tiziana; Frizzi, Benedetta; Angeli, Elena; Bazzurro, Virginia; Zara, Federico; Van Den Bosch, Ludo; Ferraiuolo, Laura; J Shaw, Pamela; Bonanno, Giambattista; Milanese, Marco | |
| Reactive Astrocytes from patients affected by Amyotrophic Lateral Sclerosis: how mGlu5 receptor modulation affects pathological features | 1-gen-2024 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Ravera, Silvia; Musante, Ilaria; Bonifacino, Tiziana; Angeli, Elena; Shaw, Allan; J Shaw, Pamela; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco | |
| Reactive phenotype and oxidative stress in i-Astrocytes from patients affected by Amyotrophic Lateral Sclerosis: how the mGluR5 negative allosteric modulator CTEP affects these pathological features | 1-gen-2023 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Ravera, Silvia; Musante, Ilaria; Bonifacino, Tiziana; Angeli, Elena; Shaw, Allan; Pamela, J Shaw; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco | |
| The negative allosteric modulator CTEP ameliorates the reactive phenotype of iastrocytes from patients affected by Amyotrophic Lateral Sclerosis | 1-gen-2022 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Shaw, Allan; Pamela, J Shaw; Bonanno, Giambattista; Milanese, Marco | |
| The negative allosteric modulator CTEP ameliorates the reactive phenotype of human-derived iAstrocytes differentiated from iNPCs of patients affected by Amyotrophic Lateral Sclerosis | 1-gen-2022 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Bonifacino, Tiziana; Shaw, Allan; Bacchetti, Francesca; Pamela, J Shaw; Ferraiuolo, Laura; Bonanno, Giambattista; Milanese, Marco | |
| The negative allosteric modulator CTEP ameliorates the reactive phenotype of iastrocytes from patients affected by Amyotrophic Lateral Sclerosis | 1-gen-2022 | Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Allan, Shaw; Pamela, J Shaw; Laura, Ferraiuolo; Bonanno, Giambattista; Milanese, Marco |