IRIS
MORETTA, LORENZO
 Distribuzione geografica
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Continente #
EU - Europa 56.378
Totale 56.378
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Nazione #
IT - Italia 56.378
Totale 56.378
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Città #
Genova 46.502
Rapallo 5.525
Genoa 4.049
Vado Ligure 182
Bordighera 120
Totale 56.378
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Nome #
Mesenchymal stem cell-Natural Killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. 186
PVR(CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis 182
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 177
Identification of cytomegalovirus (CMV)-specific T lymphocytes displaying an effector-memory phenotype that kill CMV-infected target cells in an HLA-E-restricted fashion 172
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function 167
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112) 162
NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short-term IL-2 activation. 161
T cell nature of some lymphokine-activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells. 153
Activating KIRs and NKG2C in viral infections: Toward NK cell memory? 152
Interactions Between Mesenchymal Stem Cells and Dendritic Cells. 149
Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches. 148
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2 148
New miRNA signature heralds human NK cell subsets at different maturation steps: Involvement of miR-146a-5p in the regulation of KIR expression 147
B cell growth factor activity of immunoaffinity-purified and recombinant human interleukin 2. 144
Human NK cell receptors/markers: A tool to analyze NK cell development, subsets and function. 144
Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus? 143
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 143
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2 142
Both CD133(+) and CD133(-) medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity 141
T gamma delta cells and their subsets in blood and synovial tissue from rheumatoid arthritis patients. 141
Human NK cells at early stages of differentiation produce large amounts of CXCL8 and express CD161 molecule that that functions as an activating receptor 138
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation. 138
Identification of NKp80, a novel triggering molecule expressed by human NK cells. 137
2B4 functions as a co-receptor in human NK cell activation 137
Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors. 136
Separation, phenotyping and limiting dilution analysis of T-lymphocytes infiltrating human solid tumors. 136
Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation. 135
Effect of tumor cells and tumor microenvironment on NK-cell function. 135
Stimulatory receptors in NK and T cells. 134
Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias 134
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. 133
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation. 133
Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor 133
Phenotypic and functional analysis of the HLA-class I-specific inhibitory receptors of natural killer cells isolated from peripheral blood of patients undergoing bone marrow transplantation from matched unrelated donors. 132
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. 132
Haploidentical Haematopoietic Stem Cell Transplantation: Role of NK Cells and Effect of Cytomegalovirus Infections 131
Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment. 130
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes. 130
Unique Eomes+ NK cell subsets are present in uterus and decidua during early pregnancy 130
Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. 129
Human dendritic cells activate resting Natural Killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells. 129
Surface antigens specifically expressed by activated T cells in humans. 129
IL-1β inhibits ILC3 while favoring NK-cell maturation of umbilical cord blood CD34(+) precursors 129
Interferon-γ-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus. 129
Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice. 128
Expression and crystallographic characterization of the extracellular domain of human Natural Killer cell triggering receptor NKp46 128
Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function 127
Expression of HLA-class I-specific inhibitory Natural Killer cell receptors in HIV-specific cytolytic T lymphocytes. Impairment of specific cytolytic functions. 126
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction. 126
Familial hemophagocytic lymphohistiocytosis: a model for understanding the human machinery of cellular cytotoxicity. 126
HO-1 up-regulation: A key point in high-risk neuroblastoma resistance to bortezomib. 126
Methylprednisolone induces preferential and rapid differentiation of CD34+ cord blood precursors toward NK cells. 125
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses 125
The effects of IgM rheumatoid factor on EAM and EAG rosette formation with Fc receptor-bearing lymphoid cells. 125
Bispecific monoclonal antibodies directed to CD16 and to a tumor-associated antigen induce target-cell lysis by resting NK cells and by a subset of NK clones. 125
Human Natural Killer Cells exposed to IL-2, IL12, IL-18 or IL-4 differently modulate priming of naïve T cells by monocyte-derived Dendritic Cells. 125
Human NK Cells: From Surface Receptors to the Therapy of Leukemias and Solid Tumors. 125
Extending killer Ig-like receptor function: from HLA class I recognition to sensors of microbial products 124
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells 124
NCR + ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures 124
Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors. 124
Human innate lymphoid cells 124
Surface receptors that regulate the NK cell function: beyond the NK cell scope. 123
Immunobiology of human NK cells. 123
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function. 123
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. 123
In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors. 123
Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells 123
Successfully treated HIV-infected patients have differential expression of NK cell receptors (NKp46 and NKp30) according to AIDS status at presentation. 123
Dendritic cell editing by natural killer cells. 123
Role of Nrf2, HO-1 and GSH in neuroblastoma cell resistance to bortezomib 123
Increased natural cytotoxicity receptor expression and relevant IL-10 production in NK cells from chronically infected viremic HCV patients 123
Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15. 123
Activating NK cell receptor expression/function (NKp30, NKp46, DNAM-1) during chronic viraemic HCV infection is associated with the outcome of combined treatment. 123
Role of Ia Antigens in the human autologous mixed lymphocyte reaction. 122
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK cell function 122
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells 122
Induction of anti-tumor immune response by bispecific monoclonal antibodies (bimAbs). 122
Stromal cells from human decidua exert a strong inhibitory effect on NK cell function and dendritic cell differentiation 122
KIR and KIR ligand polymorphism: a new area for clinical applications? 122
CD34+ hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells. 121
Alloreactive natural killer cells in targeting high-risk leukaemias. 121
Thymic origin of some natural killer cells: clonal proliferation of human CD3-16+ cells from CD3-4-8- thymocyte precursors requires the presence of H9 leukemic cells. 121
Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations. 120
The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors. 120
Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function. 120
Surface markers of resting and activated human T cells. Functional implications and experimental limits. 120
Analysis of the role of interferon-gamma, interleukin 2 and a third factor distinct from interferon-gamma and interleukin 2 in human B cell proliferation. Evidence that they act at different times after B cell activation. 120
M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages 120
MSC and innate immune cell interactions: A lesson from human decidua 120
Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: Engagement of CD33 induces apoptosis of leukemic cells 120
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells 120
Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias. 119
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 119
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. 119
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NK p30 119
P49, a putative HLA-G1 specific inhibitory NK receptor belonging to the immunoglobulin Superfamily. 119
Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response. 119
CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules. 118
Natural killer alloeffector responses in haploidentical hemopoietic stem cell transplantation to treat high-risk leukemias. 118
Totale 13.149
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Categoria #
all - tutte 145.468
article - articoli 138.076
book - libri 191
conference - conferenze 4.699
curatela - curatele 0
other - altro 0
patent - brevetti 848
selected - selezionate 0
volume - volumi 1.654
Totale 290.936
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202015.686 0 450 743 1.053 1.539 1.606 2.592 1.081 1.464 2.777 1.717 664
2020/20213.948 235 408 319 280 230 417 182 350 386 445 349 347
2021/20227.215 208 533 780 816 378 316 413 1.714 240 661 278 878
2022/20236.609 703 374 94 656 1.098 1.296 6 538 1.187 45 533 79
2023/20243.025 148 457 88 402 296 514 130 172 217 68 172 361
2024/2025248 146 102 0 0 0 0 0 0 0 0 0 0
Totale 56.949