IRIS
SONCINI, DEBORA
 Distribuzione geografica
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Continente #
EU - Europa 4.046
Totale 4.046
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Nazione #
IT - Italia 4.046
Totale 4.046
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Città #
Genova 2.844
Rapallo 497
Genoa 478
Vado Ligure 220
Bordighera 7
Totale 4.046
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Nome #
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 178
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 177
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 175
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 173
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 170
Ras-induced resistance to lapatinib is overcome by MEK inhibition 149
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 144
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 143
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 143
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 139
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 133
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 132
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 132
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 131
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 128
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 122
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 122
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 120
Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. 119
Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. 114
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 109
Exploiting tumor vulnerabilities: NAD+-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies 106
The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs 105
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors 101
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 94
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 90
Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma 90
Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 89
SIRT6 inhibition as a novel approach for treating Acute Myeloid Leukemia 86
Synergistic Interaction Between P-glycoprotein Inhibitors and APO866 in Primary Leukemic Cells 78
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 64
Potent Synergistic Activity of the NAD plus Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia. 63
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment 59
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 56
Dual NAMPT and BTK targeting leads to synergistic killing of Waldenström macroglobulinemia cells regardless of MYD88 and CXCR4 somatic mutation status 52
Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells 26
Therapeutic activation of G protein-coupled estrogen receptor 1 in Waldenström Macroglobulinemia 13
Targeting the immune microenvironment in Waldenström Macroglobulinemia via halting the CD40/CD40-ligand axis 7
EXTRACELLULAR NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) ARRESTS ENDOTHELIAL CELL PROLIFERATION 4
Totale 4.136
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Categoria #
all - tutte 12.820
article - articoli 12.806
book - libri 0
conference - conferenze 14
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.640
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020881 0 0 0 0 102 151 149 94 100 151 106 28
2020/2021372 27 28 22 24 47 27 28 39 26 44 41 19
2021/2022466 15 21 35 74 18 36 22 97 20 39 28 61
2022/2023603 55 59 10 92 101 72 8 43 83 9 63 8
2023/2024358 10 28 15 52 34 78 14 45 13 3 15 51
2024/2025251 37 61 16 81 56 0 0 0 0 0 0 0
Totale 4.136