IRIS
MELLONI, EDON
 Distribuzione geografica
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Continente #
EU - Europa 22.994
Totale 22.994
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Nazione #
IT - Italia 22.994
Totale 22.994
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Città #
Genova 19.018
Rapallo 2.408
Genoa 1.539
Bordighera 29
Totale 22.994
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 154
Role of the calpain-calpastatin system in the density-dependent growth arrest 149
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 147
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 146
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 145
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 143
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 143
The calpain-calpastatin system in mammalian cells: properties and possible functions 140
Effect of extremely low frequency magnetic fields on calpain activation 140
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 139
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 139
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 139
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 138
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 138
Molecular events involved in the activation of calpain from human erythrocytes 136
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 134
Conformational changes of calpain from human erythrocytes in the presence of Ca2+. 133
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 133
Extralysosomal protein degradation. 132
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 130
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 130
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 130
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels 128
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 128
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 127
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 127
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 126
Pathological role of the calpain/calpastatin system in cystic fibrosis 126
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 126
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 125
Characterization of a new p94-like calpain form in human lymphocytes 125
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 125
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 124
Fructose-1, 6-diphosphatase from rabbit liver. 124
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 124
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 122
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 122
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 122
Properties and intracellular localization of calpain activator protein 122
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 122
Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment 121
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 121
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 120
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 120
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 120
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 118
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 117
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 117
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 117
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 117
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 117
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate 116
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 116
Acyl-CoA-binding protein is a potent m-calpain activator 115
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 115
IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent 115
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 114
Rabbit liver fructose 1,6-diphosphatase. Properties of the native enzyme and their modification by subtilisin. 114
Depletion of protein kinase C induced by an anti HLA class I monoclonal antibody in phytohemagglutinin activated human T cells. 114
The carboxy-terminal amino acid sequence of rabbit liver fructose 1,6-bisphosphatase. 114
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 113
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 113
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 112
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 112
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 112
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 112
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 111
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 111
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 111
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 111
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 110
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 110
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 110
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 109
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 109
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 109
Role of calpain-1 in the early phase of experimental ALS 109
The liver aldolase-fructose bisphosphatase complex. 108
Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions. 108
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 108
Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase. 108
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 108
Fructose 1,6-bisphosphatase: properties of the neutral enzyme and its modification by proteolytic enzymes. 107
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 107
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 106
Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease 106
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 106
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 106
Endogenous inhibitors of lysosomal proteinases 106
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 105
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 105
Mechanisms of perturbation of erythrocyte calcium homeostasis in favism 104
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 104
Isolation and characterization of calpain activator protein from bovine brain. 103
Structural studies on fructose- 1,6-bisphosphatases from rabbit liver, kidney, and muscle. 103
Origin of tryptophan in fructose 1,6-bisphosphatase purified from livers of fed rabbits. 103
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 103
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 103
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 102
Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats. 102
Totale 11.946
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Categoria #
all - tutte 52.343
article - articoli 46.468
book - libri 362
conference - conferenze 4.515
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 998
Totale 104.686
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.445 0 0 0 0 0 0 0 0 0 287 629 529
2019/20206.644 277 195 369 422 602 674 959 420 576 1.126 772 252
2020/20211.474 87 134 107 95 92 144 84 136 144 160 139 152
2021/20222.829 66 187 195 313 122 186 209 610 130 291 117 403
2022/20232.879 260 168 27 370 450 563 1 197 526 13 267 37
2023/20241.100 66 181 13 141 172 316 49 51 78 33 0 0
Totale 23.161