IRIS
MELLONI, EDON
 Distribuzione geografica
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Continente #
EU - Europa 22114
Totale 22114
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Nazione #
IT - Italia 22114
Totale 22114
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Città #
Genova 19018
Rapallo 2660
Genoa 436
Totale 22114
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Nome #
Role of the calpain-calpastatin system in the density-dependent growth arrest 146
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 146
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 144
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 141
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 140
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 139
Molecular events involved in the activation of calpain from human erythrocytes 136
Effect of extremely low frequency magnetic fields on calpain activation 136
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 136
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 135
The calpain-calpastatin system in mammalian cells: properties and possible functions 135
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 134
Extralysosomal protein degradation. 133
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 133
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 133
Conformational changes of calpain from human erythrocytes in the presence of Ca2+. 132
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 132
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 129
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 128
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 126
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 126
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 125
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 125
Pathological role of the calpain/calpastatin system in cystic fibrosis 124
Fructose-1, 6-diphosphatase from rabbit liver. 123
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 123
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 123
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 122
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 122
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 122
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 122
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 121
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 120
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels 120
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 119
Properties and intracellular localization of calpain activator protein 119
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 118
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 117
Characterization of a new p94-like calpain form in human lymphocytes 117
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 117
Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment 115
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 115
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 115
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 115
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 115
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 115
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 114
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 114
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 113
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 113
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 112
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 111
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 111
Acyl-CoA-binding protein is a potent m-calpain activator 111
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 111
IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent 111
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 110
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 110
Depletion of protein kinase C induced by an anti HLA class I monoclonal antibody in phytohemagglutinin activated human T cells. 110
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 109
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 109
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 109
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 108
The carboxy-terminal amino acid sequence of rabbit liver fructose 1,6-bisphosphatase. 108
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 108
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 108
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 107
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 107
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate 106
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 105
Role of calpain-1 in the early phase of experimental ALS 105
Fructose 1,6-bisphosphatase: properties of the neutral enzyme and its modification by proteolytic enzymes. 104
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 104
Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease 104
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 104
Endogenous inhibitors of lysosomal proteinases 104
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 104
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 103
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 103
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 103
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 103
Mechanisms of perturbation of erythrocyte calcium homeostasis in favism 102
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 102
Rabbit liver fructose 1,6-diphosphatase. Properties of the native enzyme and their modification by subtilisin. 102
The liver aldolase-fructose bisphosphatase complex. 102
Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions. 102
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 102
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 102
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 102
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 102
THE CALPAIN-CALPaSTATIN SYSTEM: STRUCTURAL AND FUNCTIONAL PROPERTIES 101
Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats. 100
Structural studies on fructose- 1,6-bisphosphatases from rabbit liver, kidney, and muscle. 100
Origin of tryptophan in fructose 1,6-bisphosphatase purified from livers of fed rabbits. 100
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 100
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 99
Isolation and characterization of calpain activator protein from bovine brain. 99
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 99
Evidence for the modification of fructose 1,6-bisphosphatase by two distinct lysosomal proteases. 99
Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase. 99
Totale 11519
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Categoria #
all - tutte 35873
article - articoli 31938
book - libri 248
conference - conferenze 2970
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 717
Totale 71746
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201860 0000 00 00 00060
2018/20191836 8324411 37197 4210 10287629529
2019/20206644 277195369422 602674 959420 5761126772252
2020/20211474 8713410795 92144 84136 144160139152
2021/20222829 66187195313 122186 209610 130291117403
2022/20233099 26016827370 450563 9404 546232763
Totale 22281