Nome |
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Altered glucose catabolism in the presynaptic and perisynaptic compartments of SOD1G93A mouse spinal cord and motor cortex indicates that mitochondria are the site of bioenergetic imbalance in ALS, file e268c4ca-17af-a6b7-e053-3a05fe0adea1
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201
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Metabotropic glutamate receptor 5 as a potential target in ALS, file e268c4c9-0465-a6b7-e053-3a05fe0adea1
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154
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Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosis at a Pre-Symptomatic Stage of the Disease., file e268c4c8-bb45-a6b7-e053-3a05fe0adea1
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115
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Metabotropic glutamate receptor 5 as a potential target in ALS, file e268c4c9-0466-a6b7-e053-3a05fe0adea1
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111
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Chronic mild stress induces anhedonic behavior and changes in glutamate release, BDNF trafficking and dendrite morphology only in stress vulnerable rats. The rapid restorative action of ketamine, file e268c4ca-15ea-a6b7-e053-3a05fe0adea1
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108
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Prophylactic versus therapeutic fingolimod: Restoration of presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis, file e268c4ca-2404-a6b7-e053-3a05fe0adea1
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104
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Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia, file e268c4ce-fa95-a6b7-e053-3a05fe0adea1
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104
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Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression, file e268c4ca-ac9c-a6b7-e053-3a05fe0adea1
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93
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Differential expression of metabotropic glutamate and GABA receptors at neocortical glutamatergic and GABAergic axon terminals, file e268c4ca-8436-a6b7-e053-3a05fe0adea1
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77
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Characterization of the Mitochondrial Aerobic Metabolism in the Pre- and Perisynaptic Districts of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis, file e268c4cf-09ae-a6b7-e053-3a05fe0adea1
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63
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Acute Footshock Stress Induces Time-Dependent Modifications of AMPA/NMDA Protein Expression and AMPA Phosphorylation, file e268c4cd-9319-a6b7-e053-3a05fe0adea1
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57
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In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1G93A mouse model of amyotrophic lateral sclerosis., file e268c4ce-d924-a6b7-e053-3a05fe0adea1
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47
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Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice, file e268c4cc-1945-a6b7-e053-3a05fe0adea1
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46
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Metabotropic glutamate receptor 5 as a potential target in ALS, file e268c4c9-2cec-a6b7-e053-3a05fe0adea1
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42
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Exosome-shuttled miRNAs derived from mesenchymal stem cells modulate in-vitro the reactive phenotype of amyotrophic lateral sclerosis glial cell, file e268c4cd-8db5-a6b7-e053-3a05fe0adea1
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34
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Altered mechanisms underlying the abnormal glutamate release in amyotrophic lateral sclerosis at a pre-symptomatic stage of the disease, file e268c4ce-cd53-a6b7-e053-3a05fe0adea1
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28
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Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosis at a Pre-Symptomatic Stage of the Disease., file e268c4c8-6caa-a6b7-e053-3a05fe0adea1
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21
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Insights into Human-Induced Pluripotent Stem Cell-Derived Astrocytes in Neurodegenerative Disorders, file e268c4ce-e05c-a6b7-e053-3a05fe0adea1
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18
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In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis, file e268c4ce-bf07-a6b7-e053-3a05fe0adea1
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17
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Intravenous mesenchymal stem cells administration induces survival and symptom amelioration in mutant SOD1 G93A mice, file e268c4c8-b239-a6b7-e053-3a05fe0adea1
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16
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Molecular mechanisms supporting abnormal glutamate release in the spinal cord of a mouse model of Amyotrophic Lateral Sclerosis., file e268c4c8-ad39-a6b7-e053-3a05fe0adea1
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15
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Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosisat a Pre-Symptomatic Stage of the Disease., file e268c4c8-ad36-a6b7-e053-3a05fe0adea1
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14
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Alterations of Synaptic Mechanisms and Excessive Glutamate Release in the Spinal Cord of SOD1G93A Mice, file e268c4c8-af87-a6b7-e053-3a05fe0adea1
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14
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Metabotropic glutamate receptor type 5 effects on ALS progression, file e268c4cb-8e1d-a6b7-e053-3a05fe0adea1
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14
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Multiple neuron clusters on Micro-Electrode Arrays as an in vitro model of brain network, file 55b129ad-ed3d-4280-888d-b2ca87b9a0d4
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13
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Alterations of Synaptic Mechanisms and Excessive Glutamate Release in the Spinal Cord of SOD1G93A Mice, file e268c4c8-ad42-a6b7-e053-3a05fe0adea1
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13
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Intravenous mesenchymal stem cells administration induces survival and symptom amelioration in mutant SOD1 G93A mice, file e268c4c8-b1d5-a6b7-e053-3a05fe0adea1
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13
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Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein, file e268c4c5-faa7-a6b7-e053-3a05fe0adea1
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11
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The GABAergic-like system in the cyprid of Balanus amphitrite (=Amphibalanus amphitrite) (Cirripedia, Crustacea), file e268c4c6-14e3-a6b7-e053-3a05fe0adea1
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11
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Synaptic Mechanisms Sustaining The Excessive And Precocious Glutamate Release In The Spinal Cord Of SOD1G93A Mice, file e268c4c8-af8a-a6b7-e053-3a05fe0adea1
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10
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Non conventional activity of the endocannabinoid system at glutamate release in rat cortical astrocytes, file e268c4c8-b011-a6b7-e053-3a05fe0adea1
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9
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Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis, file e268c4cc-abb7-a6b7-e053-3a05fe0adea1
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9
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Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation, file e268c4cd-919d-a6b7-e053-3a05fe0adea1
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9
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Nearly 30 years of animal models to study amyotrophic lateral sclerosis: A historical overview and future perspectives., file e268c4ce-4158-a6b7-e053-3a05fe0adea1
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9
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Reducing mglur5 expression attenuates the reactive phenotype of astrocytes cultured from the spinal cord of late symptomatic SOD1G93A mice, file e268c4cb-a224-a6b7-e053-3a05fe0adea1
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8
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Partial deletion of mGluR5 affects M1 and M2 phenotypes in microglia acutely isolated from SOD1(G93A) mice during disease progression, file e268c4cb-a3d1-a6b7-e053-3a05fe0adea1
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8
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Axonal GABAA stabilizes excitability in unmyelinated sensory axons secondary to NKCC1 activity, file e268c4ce-54eb-a6b7-e053-3a05fe0adea1
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8
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The Role of Endoplasmic Reticulum in the Differential Endurance against Redox Stress in Cortical and Spinal Astrocytes from the Newborn SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis, file e268c4ce-62d6-a6b7-e053-3a05fe0adea1
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8
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Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress, file 723e031a-e913-4838-92b7-0cc56fecdc2e
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7
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Synaptic mechanisms underlying the excessive and precocious glutamate release in the spinal cord of sod1g93a mice., file e268c4c8-b787-a6b7-e053-3a05fe0adea1
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7
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A multistationary loop model of ALS unveils critical molecular interactions involving mitochondria and glucose metabolism, file e268c4cd-7e11-a6b7-e053-3a05fe0adea1
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7
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In vitro Evidence of Abnormal Glutamate to Glutamine Conversion in Astrocytes harvested from a Mouse Model of Amyotrophic Lateral Sclerosis: a potential Experimental Application of N-13-ammonia, file e268c4cb-8415-a6b7-e053-3a05fe0adea1
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6
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Effect of miRNAs shuttled by exosomes derived from primed-MSCs on activated-microglia phenotype and possible implication in amyotrophic lateral sclerosis., file e268c4c8-b780-a6b7-e053-3a05fe0adea1
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5
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Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS, file 3965d2c2-4fec-4778-ad79-622f3580c88e
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4
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Adult astroglia is competent for Na+/Ca2+ exchanger-operated exocytotic glutamate release triggered by mild depolarization, file e268c4c5-f6c2-a6b7-e053-3a05fe0adea1
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4
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Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by ‘pathologically’ elevated extraterminal K+ concentrations, file e268c4c5-f6c5-a6b7-e053-3a05fe0adea1
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4
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Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosisat a Pre-Symptomatic Stage of the Disease., file e268c4c8-ad37-a6b7-e053-3a05fe0adea1
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4
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Effect of miRNAs shuttled by exosomes derived from primed-MSCs on activated-microglia phenotype and possible implication in amyotrophic lateral sclerosis., file e268c4c8-af79-a6b7-e053-3a05fe0adea1
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4
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Knocking-down mGluR1 and mGluR5 in SOD1G93A mice ameliorates survival and disease progression, file e268c4c8-bae6-a6b7-e053-3a05fe0adea1
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4
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Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission., file e268c4ca-1890-a6b7-e053-3a05fe0adea1
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4
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Effects of the GPR17 antagonist montelukast on oligodendrocyte dysfunction and disease outcome in the SOD1G93A mouse model of ALS, file e268c4ce-1392-a6b7-e053-3a05fe0adea1
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4
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Imidazo-Pyrazole-Loaded Palmitic Acid and Polystyrene-Based Nanoparticles: Synthesis, Characterization and Antiproliferative Activity on Chemo-Resistant Human Neuroblastoma Cells, file 280482bc-170f-4dcf-ab42-72da66d82889
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3
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A repurposing approach to improve disease outcome in SOD1G93A mice by counteracting oligodendrocyte dysfunction and neuroinflammation, file 86fe5d1d-64df-4c7f-aab4-a875866edb07
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3
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Group I metabotropic glutamate autoreceptors induce abnormal glutamate exocytosis in a mouse model of amyotrophic lateral sclerosis, file e268c4c7-f9c8-a6b7-e053-3a05fe0adea1
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3
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Intravenous mesenchymal stem cells administration induces survival and symptom amelioration in mutant SOD1 G93A mice, file e268c4c8-b23a-a6b7-e053-3a05fe0adea1
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3
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Altered synaptic mechanisms and excessive glutamate release in amyotrophic lateral sclerosis, file e268c4c8-ec02-a6b7-e053-3a05fe0adea1
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3
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In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis, file e268c4ca-8911-a6b7-e053-3a05fe0adea1
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3
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In-vivo and in-vitro evidence supporting the role of mGlu5 receptor as a key regulator of glutamate downstream effects in ALS, file e268c4ce-237f-a6b7-e053-3a05fe0adea1
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3
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Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress, file 002976ad-664e-4f1f-a5a2-ef7c65abb4cd
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2
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Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain, file 41e1d429-5959-40b9-b071-2494ede9cc6a
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2
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Montelukast improves disease progression in the female SOD1G93A mouse model of ALS by restoring oligodendrocyte maturation and counteracting altered glial reactivity, file 52f25230-2c8c-4add-9613-fa057ab63037
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2
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In-vivo treatment with the GPR17 antagonist montelukast improves lifespan and delays disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis, file 653999f3-655a-4cb0-a1c9-a901a105df8f
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2
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Montelukast improves disease progression in the female SOD1G93A mouse model of ALS by restoring oligodendrocyte maturation and counteracting altered glial reactivity, file 6f5a9781-8886-40e6-91a1-d9a02fa0d402
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2
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The Physio-Pathological Role of Group I Metabotropic Glutamate Receptors Expressed by Microglia in Health and Disease with a Focus on Amyotrophic Lateral Sclerosis, file 9938f52d-d129-4d81-b3ff-e80cd472bbca
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2
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The GPR17 receptor as a new potential pharmacological target to restore oligodendroglial dysfunction in amyotrophic lateral sclerosis, file e268c4c9-046a-a6b7-e053-3a05fe0adea1
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2
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Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia, file e268c4ca-1fcd-a6b7-e053-3a05fe0adea1
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2
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Characterization of the Mitochondrial Aerobic Metabolism in the Pre- and Perisynaptic Districts of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis, file e268c4ca-40e1-a6b7-e053-3a05fe0adea1
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2
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Altered intracellular calcium homeostasis underlying enhanced glutamatergic transmission in striatal-enriched tyrosine phosphatase (STEP) knockout mice, file e268c4ca-4b1f-a6b7-e053-3a05fe0adea1
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2
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Knocking-down mGluR1 and mGluR5 in the SOD1/G93A mouse model of amyotrophic lateral sclerosis ameliorates survival and disease progression, file e268c4cb-d881-a6b7-e053-3a05fe0adea1
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2
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Acute Ketamine Facilitates Fear Memory Extinction in a Rat Model of PTSD Along With Restoring Glutamatergic Alterations and Dendritic Atrophy in the Prefrontal Cortex., file 0c4d4b92-a6f1-45ee-9918-88d092bb5381
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1
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Functional and Molecular Changes in the Prefrontal Cortex of the Chronic Mild Stress Rat Model of Depression and Modulation by Acute Ketamine, file 3a017fc7-c7ed-4851-a2e8-fc844f07c647
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1
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The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes, file e268c4c6-02eb-a6b7-e053-3a05fe0adea1
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1
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Role of calpain-1 in the early phase of experimental ALS, file e268c4c6-1803-a6b7-e053-3a05fe0adea1
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1
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Intravenous mesenchymal stem cells administration induces survival and symptom amelioration in mutant SOD1 G93A mice, file e268c4c8-b1d4-a6b7-e053-3a05fe0adea1
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1
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Abnormal glutamate release induced by group I metabotropic glutamate receptors in experimental ALS., file e268c4c8-bae4-a6b7-e053-3a05fe0adea1
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1
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Intravenous mesenchymal stem cells improve survival and motor functions in symptomatic mutant SOD1/G93A mice, file e268c4c8-bb54-a6b7-e053-3a05fe0adea1
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1
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Intravenous mesenchymal stem cells improve survival and motor functions in symptomatic mutant SOD1/G93A mice, file e268c4c8-bb55-a6b7-e053-3a05fe0adea1
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1
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Altered synaptic mechanisms and excessive glutamate release in amyotrophic lateral sclerosis, file e268c4c8-ec01-a6b7-e053-3a05fe0adea1
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1
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Genetic and pharmacological effects of mGlu5 receptor blockade in the SOD1G93A mouse model of amyotrophic lateral sclerosis, file e268c4c9-0468-a6b7-e053-3a05fe0adea1
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1
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Metabotropic glutamate receptor type 5 effects on ALS progression, file e268c4ca-0a30-a6b7-e053-3a05fe0adea1
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1
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Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis., file e268c4ca-188c-a6b7-e053-3a05fe0adea1
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1
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Genetic and pharmacological effects of mGlu5 receptor blockade in the SOD1G93A mouse model of amyotrophic lateral sclerosis, file e268c4cb-9369-a6b7-e053-3a05fe0adea1
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1
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The GPR17 receptor as a new potential pharmacological target to restore oligodendroglial dysfunction in amyotrophic lateral sclerosis, file e268c4cb-944d-a6b7-e053-3a05fe0adea1
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1
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In-vitro and in-vivo studies depict metabotropic glutamate receptor 5 as a potential pharmacological target to modulate disease progression in ALS, file e268c4ce-5f16-a6b7-e053-3a05fe0adea1
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1
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Altered mechanisms underlying the abnormal glutamate release in amyotrophic lateral sclerosis at a pre-symptomatic stage of the disease, file e268c4ce-ef46-a6b7-e053-3a05fe0adea1
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1
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Totale |
1.775 |