GUARIENTO, SARA
GUARIENTO, SARA
Design and synthesis of 4,5,6,7‐tetrahydro‐1H‐1,2‐diazepin‐7‐one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors
2017-01-01 Guariento, Sara; Karawajczyk, Anna; Bull, James A.; Marchini, Gessica; Bielska, Martyna; Iwanowa, Xenia; Bruno, Olga; Fossa, Paola; Giordanetto, Fabrizio
Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics
2016-01-01 D'Ursi, Pasqualina; Guariento, Sara; Trombetti, Gabriele; Orro, Alessandro; Cichero, Elena; Milanesi, Luciano; Fossa, Paola; Bruno, Olga
Ligand-based homology modelling of the human CB2 receptor SR144528 antagonist binding site: a computational approach to explore the 1,5-diaryl pyrazole scaffold
2015-01-01 Cichero, Elena; Menozzi, Giulia; Guariento, Sara; Fossa, Paola
New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies
2016-01-01 Guariento, Sara; Bruno, Olga; Fossa, Paola; Cichero, Elena
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment
2016-01-01 Brullo, Chiara; Ricciarelli, Roberta; Prickaerts, Jos; Arancio, Ottavio; Massa, Matteo; Rotolo, Chiara; Romussi, Alessia; Rebosio, Claudia; Marengo, Barbara; Pronzato, MARIA ADELAIDE; van Hagen, Britt T. J.; van Goethem, Nick P.; D'Ursi, Pasqualina; Orro, Alessandro; Milanesi, Luciano; Guariento, Sara; Cichero, Elena; Fossa, Paola; Fedele, Ernesto; Bruno, Olga
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists
2018-01-01 Guariento, Sara; Tonelli, Michele; Espinoza, Stefano; Gerasimov, Andrey S.; Gainetdinov, Raul R.; Cichero, Elena
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis
2015-01-01 Pesce, Emanuela; Bellotti, Marta; Liessi, Nara; Guariento, Sara; Damonte, Gianluca; Cichero, Elena; Galatini, Andrea; Salis, Annalisa; Gianotti, Ambra; Pedemonte, Nicoletta; Zegarra Moran, Olga; Fossa, Paola; Galietta, Luis J. V; Millo, Enrico
Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) Related Phosphodiesterase 4D (PDE4D) Inhibitors.
2014-01-01 Brullo, Chiara; Massa, Matteo; Rocca, Massimo; Rotolo, Chiara; Guariento, Sara; Rivera, Daniela; Ricciarelli, Roberta; Fedele, Ernesto; Fossa, Paola; Bruno, Olga
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Design and synthesis of 4,5,6,7‐tetrahydro‐1H‐1,2‐diazepin‐7‐one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors | 1-gen-2017 | Guariento, Sara; Karawajczyk, Anna; Bull, James A.; Marchini, Gessica; Bielska, Martyna; Iwanowa, Xenia; Bruno, Olga; Fossa, Paola; Giordanetto, Fabrizio | |
| Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics | 1-gen-2016 | D'Ursi, Pasqualina; Guariento, Sara; Trombetti, Gabriele; Orro, Alessandro; Cichero, Elena; Milanesi, Luciano; Fossa, Paola; Bruno, Olga | |
| Ligand-based homology modelling of the human CB2 receptor SR144528 antagonist binding site: a computational approach to explore the 1,5-diaryl pyrazole scaffold | 1-gen-2015 | Cichero, Elena; Menozzi, Giulia; Guariento, Sara; Fossa, Paola | |
| New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies | 1-gen-2016 | Guariento, Sara; Bruno, Olga; Fossa, Paola; Cichero, Elena | |
| New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment | 1-gen-2016 | Brullo, Chiara; Ricciarelli, Roberta; Prickaerts, Jos; Arancio, Ottavio; Massa, Matteo; Rotolo, Chiara; Romussi, Alessia; Rebosio, Claudia; Marengo, Barbara; Pronzato, MARIA ADELAIDE; van Hagen, Britt T. J.; van Goethem, Nick P.; D'Ursi, Pasqualina; Orro, Alessandro; Milanesi, Luciano; Guariento, Sara; Cichero, Elena; Fossa, Paola; Fedele, Ernesto; Bruno, Olga | |
| Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists | 1-gen-2018 | Guariento, Sara; Tonelli, Michele; Espinoza, Stefano; Gerasimov, Andrey S.; Gainetdinov, Raul R.; Cichero, Elena | |
| Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis | 1-gen-2015 | Pesce, Emanuela; Bellotti, Marta; Liessi, Nara; Guariento, Sara; Damonte, Gianluca; Cichero, Elena; Galatini, Andrea; Salis, Annalisa; Gianotti, Ambra; Pedemonte, Nicoletta; Zegarra Moran, Olga; Fossa, Paola; Galietta, Luis J. V; Millo, Enrico | |
| Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) Related Phosphodiesterase 4D (PDE4D) Inhibitors. | 1-gen-2014 | Brullo, Chiara; Massa, Matteo; Rocca, Massimo; Rotolo, Chiara; Guariento, Sara; Rivera, Daniela; Ricciarelli, Roberta; Fedele, Ernesto; Fossa, Paola; Bruno, Olga |