L-asparaginase is an enzyme clinically accepted as an anti-tumor agent for the treatment of acute lymphoblastic leukemia and lymphosarcoma. The main focus of this study is to provide a thorough overview on microbial production of such a biopharmaceutical.
Production of extracellular l-asparaginase: from bioprospecting to the engineering of an antileukemic biopharmaceutical
CONVERTI, ATTILIO;
2014-01-01
Abstract
L-asparaginase is an enzyme clinically accepted as an anti-tumor agent for the treatment of acute lymphoblastic leukemia and lymphosarcoma. The main focus of this study is to provide a thorough overview on microbial production of such a biopharmaceutical.
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