180a Wednesday, February 24, 2021 ptychographic module was developed and mounted on a commercial SIM, to simultaneously collect ptychography and SIM data. We show how changes in the morphology of a HGPS nucleus affect the phase compared to normal cells, and how the SIM-ptychography approach can increase the resolution compared with conventional optical ptychography.
Sim-Ptychography Imaging of Hutchinson-Gilford Progeria Syndrome (HGPS) Cells
Trianni, Alberta;Cainero, Isotta;Diaspro, Alberto
2021-01-01
Abstract
180a Wednesday, February 24, 2021 ptychographic module was developed and mounted on a commercial SIM, to simultaneously collect ptychography and SIM data. We show how changes in the morphology of a HGPS nucleus affect the phase compared to normal cells, and how the SIM-ptychography approach can increase the resolution compared with conventional optical ptychography.
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