SCARANO, NAOMI
SCARANO, NAOMI
100019 - Dipartimento di chimica e chimica industriale
A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation
2024-01-01 Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S.
Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors
2024-01-01 Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia.
Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands
2024-01-01 Scarano, N.; Espinoza, S.; Brullo, C.; Cichero, E.
COMPUTATIONAL METHODS IN THE SEARCH FOR NOVEL TAAR1 AGONISTS
2024-01-01 Scarano, Naomi
Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
2024-01-01 Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S.
Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays
2024-01-01 Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E.
In Silico and In Vitro Evaluation of the Mechanism of Action of Three VX809-Based Hybrid Derivatives as Correctors of the F508del CFTR Protein
2023-01-01 Baroni, D.; Scarano, N.; Ludovico, A.; Brandas, C.; Parodi, A.; Lunaccio, D.; Fossa, P.; Moran, O.; Cichero, E.; Millo, E.
In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists
2024-01-01 Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR).
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Origlia, Nicola; Musumeci, Francesca; Schenone, Silvia; Spinelli, Sonia; Passalacqua, Mario; Zocchi, Elena; Sturla, Laura; Cichero, Elena; Cavalli, Andrea
Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays
2023-01-01 Abbotto, Elena; Casini, Beatrice; Piacente, Francesco; Scarano, Naomi; Cerri, Elena; Tonelli, Michele; Astigiano, Cecilia; Millo, Enrico; Sturla, Laura; Bruzzone, Santina; Cichero, Elena
Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction
2023-01-01 Asproni, Battistina; Catto, Marco; Loriga, Giovanni; Murineddu, Gabriele; Corona, Paola; Purgatorio, Rosa; Cichero, Elena; Fossa, Paola; Scarano, Naomi; Martínez, Antón L.; Brea, José; Pinna, Gérard A.
Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective
2024-01-01 Scarano, Naomi; Brullo, Chiara; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena
Scouting in silico different chemo-types of PDE4 inhibitors to guide the design of new anti-inflammatory/antioxidant agents
2023-01-01 Cichero, Elena; Rapetti, Federica; Lusardi, Matteo; Scarano, Naomi; Alfei, Silvana; Altieri, Paola; Garibaldi, Silvano; Ameri, Pietro; Signorello, MARIA GRAZIA; Brullo, Chiara
Structure-Based Virtual Screening (SBVS) for the discovery of Sirtuin-2 inhibitors
2024-01-01 Scarano, Naomi; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena
Structure-Based Virtual Screening (SBVS) in flexible systems: the case of SIRT-2
2022-01-01 Scarano, Naomi; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena
Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors
2023-01-01 Scarano, N.; Abbotto, E.; Musumeci, F.; Salis, A.; Brullo, C.; Fossa, P.; Schenone, S.; Bruzzone, S.; Cichero, E.
Virtual Screening in the Identification of Sirtuins' Activity Modulators
2022-01-01 Abbotto, Elena; Scarano, Naomi; Piacente, Francesco; Millo, Enrico; Cichero, Elena; Bruzzone, Santina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation | 1-gen-2024 | Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S. | |
| Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors | 1-gen-2024 | Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia. | |
| Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands | 1-gen-2024 | Scarano, N.; Espinoza, S.; Brullo, C.; Cichero, E. | |
| COMPUTATIONAL METHODS IN THE SEARCH FOR NOVEL TAAR1 AGONISTS | 1-gen-2024 | Scarano, Naomi | |
| Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena | |
| Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling | 1-gen-2024 | Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S. | |
| Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays | 1-gen-2024 | Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E. | |
| In Silico and In Vitro Evaluation of the Mechanism of Action of Three VX809-Based Hybrid Derivatives as Correctors of the F508del CFTR Protein | 1-gen-2023 | Baroni, D.; Scarano, N.; Ludovico, A.; Brandas, C.; Parodi, A.; Lunaccio, D.; Fossa, P.; Moran, O.; Cichero, E.; Millo, E. | |
| In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists | 1-gen-2024 | Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR). | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Origlia, Nicola; Musumeci, Francesca; Schenone, Silvia; Spinelli, Sonia; Passalacqua, Mario; Zocchi, Elena; Sturla, Laura; Cichero, Elena; Cavalli, Andrea | |
| Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays | 1-gen-2023 | Abbotto, Elena; Casini, Beatrice; Piacente, Francesco; Scarano, Naomi; Cerri, Elena; Tonelli, Michele; Astigiano, Cecilia; Millo, Enrico; Sturla, Laura; Bruzzone, Santina; Cichero, Elena | |
| Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction | 1-gen-2023 | Asproni, Battistina; Catto, Marco; Loriga, Giovanni; Murineddu, Gabriele; Corona, Paola; Purgatorio, Rosa; Cichero, Elena; Fossa, Paola; Scarano, Naomi; Martínez, Antón L.; Brea, José; Pinna, Gérard A. | |
| Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective | 1-gen-2024 | Scarano, Naomi; Brullo, Chiara; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena | |
| Scouting in silico different chemo-types of PDE4 inhibitors to guide the design of new anti-inflammatory/antioxidant agents | 1-gen-2023 | Cichero, Elena; Rapetti, Federica; Lusardi, Matteo; Scarano, Naomi; Alfei, Silvana; Altieri, Paola; Garibaldi, Silvano; Ameri, Pietro; Signorello, MARIA GRAZIA; Brullo, Chiara | |
| Structure-Based Virtual Screening (SBVS) for the discovery of Sirtuin-2 inhibitors | 1-gen-2024 | Scarano, Naomi; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena | |
| Structure-Based Virtual Screening (SBVS) in flexible systems: the case of SIRT-2 | 1-gen-2022 | Scarano, Naomi; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena | |
| Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors | 1-gen-2023 | Scarano, N.; Abbotto, E.; Musumeci, F.; Salis, A.; Brullo, C.; Fossa, P.; Schenone, S.; Bruzzone, S.; Cichero, E. | |
| Virtual Screening in the Identification of Sirtuins' Activity Modulators | 1-gen-2022 | Abbotto, Elena; Scarano, Naomi; Piacente, Francesco; Millo, Enrico; Cichero, Elena; Bruzzone, Santina |