ABBOTTO, ELENA
ABBOTTO, ELENA
100008 - Dipartimento di medicina sperimentale
Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays
2024-01-01 Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E.
Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances {DNA} damage
2023-01-01 Nappi, Annarita; Miro, Caterina; Pezone, Antonio; Tramontano, Alfonso; Di Cicco, Emery; Sagliocchi, Serena; Gaetana Cicatiello, Annunziata; Murolo, Melania; Torabinejad, Sepehr; Abbotto, Elena; Caiazzo, Giuseppina; Raia, Maddalena; Stornaiuolo, Mariano; Antonini, Dario; Fabbrocini, Gabriella; Salvatore, Domenico; Enrico Avvedimento, Vittorio; Dentice, Monica
Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays
2023-01-01 Abbotto, Elena; Casini, Beatrice; Piacente, Francesco; Scarano, Naomi; Cerri, Elena; Tonelli, Michele; Astigiano, Cecilia; Millo, Enrico; Sturla, Laura; Bruzzone, Santina; Cichero, Elena
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration
2020-01-01 Ferrara, G.; Benzi, A.; Sturla, L.; Marubbi, D.; Frumento, D.; Spinelli, S.; Abbotto, E.; Ivaldi, F.; Von Holtey, M.; Murone, M.; Nencioni, A.; Uccelli, A.; Bruzzone, S.
SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma
2023-01-01 Abbotto, Elena; Miro, Caterina; Piacente, Francesco; Salis, Annalisa; Murolo, Melania; Nappi, Annarita; Millo, Enrico; Russo, Eleonora; Cichero, Elena; Sturla, Laura; Del Rio, Alberto; Flora, Antonio De; Nencioni, Alessio; Dentice, Monica; Bruzzone, Santina
SIRTUIN 2 AND SIRTUIN 6 MODULATORS AS CANCER THERAPEUTICS
2023-05-12 Abbotto, Elena
Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling
2022-01-01 Mishra, Sneha; Cosentino, Claudia; Tamta, Ankit Kumar; Khan, Danish; Srinivasan, Shalini; Ravi, Venkatraman; Abbotto, Elena; Arathi, Bangalore Prabhashankar; Kumar, Shweta; Jain, Aditi; Ramaian, Anand S; Kizkekra, Shruti M; Rajagopal, Raksha; Rao, Swathi; Krishna, Swati; Asirvatham-Jeyaraj, Ninitha; Haggerty, Elizabeth R; Silberman, Dafne M; Kurland, Irwin J; Veeranna, Ravindra P; Jayavelu, Tamilselvan; Bruzzone, Santina; Mostoslavsky, Raul; Sundaresan, Nagalingam R
Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors
2023-01-01 Scarano, N.; Abbotto, E.; Musumeci, F.; Salis, A.; Brullo, C.; Fossa, P.; Schenone, S.; Bruzzone, S.; Cichero, E.
Virtual Screening in the Identification of Sirtuins' Activity Modulators
2022-01-01 Abbotto, Elena; Scarano, Naomi; Piacente, Francesco; Millo, Enrico; Cichero, Elena; Bruzzone, Santina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays | 1-gen-2024 | Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E. | |
| Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances {DNA} damage | 1-gen-2023 | Nappi, Annarita; Miro, Caterina; Pezone, Antonio; Tramontano, Alfonso; Di Cicco, Emery; Sagliocchi, Serena; Gaetana Cicatiello, Annunziata; Murolo, Melania; Torabinejad, Sepehr; Abbotto, Elena; Caiazzo, Giuseppina; Raia, Maddalena; Stornaiuolo, Mariano; Antonini, Dario; Fabbrocini, Gabriella; Salvatore, Domenico; Enrico Avvedimento, Vittorio; Dentice, Monica | |
| Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays | 1-gen-2023 | Abbotto, Elena; Casini, Beatrice; Piacente, Francesco; Scarano, Naomi; Cerri, Elena; Tonelli, Michele; Astigiano, Cecilia; Millo, Enrico; Sturla, Laura; Bruzzone, Santina; Cichero, Elena | |
| Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration | 1-gen-2020 | Ferrara, G.; Benzi, A.; Sturla, L.; Marubbi, D.; Frumento, D.; Spinelli, S.; Abbotto, E.; Ivaldi, F.; Von Holtey, M.; Murone, M.; Nencioni, A.; Uccelli, A.; Bruzzone, S. | |
| SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma | 1-gen-2023 | Abbotto, Elena; Miro, Caterina; Piacente, Francesco; Salis, Annalisa; Murolo, Melania; Nappi, Annarita; Millo, Enrico; Russo, Eleonora; Cichero, Elena; Sturla, Laura; Del Rio, Alberto; Flora, Antonio De; Nencioni, Alessio; Dentice, Monica; Bruzzone, Santina | |
| SIRTUIN 2 AND SIRTUIN 6 MODULATORS AS CANCER THERAPEUTICS | 12-mag-2023 | Abbotto, Elena | |
| Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling | 1-gen-2022 | Mishra, Sneha; Cosentino, Claudia; Tamta, Ankit Kumar; Khan, Danish; Srinivasan, Shalini; Ravi, Venkatraman; Abbotto, Elena; Arathi, Bangalore Prabhashankar; Kumar, Shweta; Jain, Aditi; Ramaian, Anand S; Kizkekra, Shruti M; Rajagopal, Raksha; Rao, Swathi; Krishna, Swati; Asirvatham-Jeyaraj, Ninitha; Haggerty, Elizabeth R; Silberman, Dafne M; Kurland, Irwin J; Veeranna, Ravindra P; Jayavelu, Tamilselvan; Bruzzone, Santina; Mostoslavsky, Raul; Sundaresan, Nagalingam R | |
| Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors | 1-gen-2023 | Scarano, N.; Abbotto, E.; Musumeci, F.; Salis, A.; Brullo, C.; Fossa, P.; Schenone, S.; Bruzzone, S.; Cichero, E. | |
| Virtual Screening in the Identification of Sirtuins' Activity Modulators | 1-gen-2022 | Abbotto, Elena; Scarano, Naomi; Piacente, Francesco; Millo, Enrico; Cichero, Elena; Bruzzone, Santina |