FRANCESCONI, VALERIA
FRANCESCONI, VALERIA
100006 - Dipartimento di Farmacia
9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp)
2018-01-01 Loddo, Roberta; Francesconi, Valeria; Laurini, Erik; Boccardo, Silvia; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina; Tonelli, Michele
Anti-α-glucosidase and antiglycation activities of α-mangostin and new xanthenone derivatives: Enzymatic kinetics and mechanistic insights through in vitro studies
2022-01-01 Djeujo, F. M.; Francesconi, V.; Gonella, M.; Ragazzi, E.; Tonelli, M.; Froldi, G.
Antitarget, Anti-SARS-CoV‑2 Leads, Drugs, and the Drug Discovery−Genetics Alliance Perspective
2023-01-01 Pozzi, Cecilia; Vanet, Anne; Francesconi, Valeria; Tagliazucchi, Lorenzo; Tassone, Giusy; Venturelli, Alberto; Spyrakis, Francesca; Mazzorana, Marco; Paola Costi, Maria; Tonelli, Michele
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives
2022-01-01 Barbieri, Federica; Bosio, Alessia Graziana; Pattarozzi, Alessandra; Tonelli, Michele; Bajetto, Adriana; Verduci, Ivan; Cianci, Francesca; Cannavale, Gaetano; Palloni, Luca M G; Francesconi, Valeria; Thellung, Stefano; Fiaschi, Pietro; Mazzetti, Samanta; Schenone, Silvia; Balboni, Beatrice; Girotto, Stefania; Malatesta, Paolo; Daga, Antonio; Zona, Gianluigi; Mazzanti, Michele; Florio, Tullio
Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays
2023-01-01 Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment
2024-01-01 Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia
Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase
2021-01-01 Tassone, G.; Landi, G.; Linciano, P.; Francesconi, V.; Tonelli, M.; Tagliazucchi, L.; Costi, M. P.; Mangani, S.; Pozzi, C.
Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA–PB1 Subunits Interaction
2024-01-01 Giacchello, Ilaria; Cianciusi, Annarita; Bertagnin, Chiara; Bonomini, Anna; Francesconi, Valeria; Mori, Mattia; Carbone, Anna; Musumeci, FRANCESCA MICHELA; Loregian, Arianna; Schenone, Silvia
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents
2024-01-01 Francesconi, V.; Rizzo, M.; Pozzi, C.; Tagliazucchi, L.; Konchie Simo, C. U.; Saporito, G.; Landi, G.; Mangani, S.; Carbone, A.; Schenone, S.; Santarem, N.; Tavares, J.; Cordeiro-Da-Silva, A.; Costi, M. P.; Tonelli, M.
Journey on naphthoquinone and anthraquinone derivatives: New insights in alzheimer’s disease
2021-01-01 Campora, M.; Francesconi, V.; Schenone, S.; Tasso, B.; Tonelli, M.
Novel 1-amidino-4-phenylpiperazines as potent agonists at human taar1 receptor: Rational design, synthesis, biological evaluation and molecular docking studies
2020-01-01 Francesconi, V.; Cichero, E.; Kanov, E. V.; Laurini, E.; Pricl, S.; Gainetdinov, R. R.; Tonelli, M.
Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents
2021-01-01 Cichero, Elena; Calautti, Alessio; Francesconi, Valeria; Tonelli, Michele; Schenone, Silvia; Fossa, Paola
State-of-the-art Review on the Antiparasitic Activity of Benzimidazole-based Derivatives: Facing Malaria, Leishmaniasis, and Trypanosomiasis
2024-01-01 Francesconi, Valeria; Rizzo, Marco; Schenone, Silvia; Carbone, Anna; Tonelli, Michele
Synthesis and biological evaluation of nitrogen heterocycle systems as potential antiviral agents
2020-03-20 Francesconi, Valeria
Synthesis and biological evaluation of novel (thio)semicarbazone-based benzimidazoles as antiviral agents against human respiratory viruses
2020-01-01 Francesconi, Valeria; Cichero, Elena; Schenone, Silvia; Naesens, Lieve; Tonelli, Michele
Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)
2018-01-01 Francesconi, Valeria; Luca, Giovannini; Santucci, Matteo; Cichero, Elena; Paola Costi, Maria; Naesens, Lieve; Giordanetto, Fabrizio; Tonelli, Michele
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease
2023-01-01 Tonelli, Michele; Catto, Marco; Sabaté, Raimon; Francesconi, Valeria; Laurini, Erik; Pricl, Sabrina; Pisani, Leonardo; Valeria Miniero, Daniela; Maria Liuzzi, Grazia; Gatta, Elena; Relini, Annalisa; Gavín, Rosalina; Antonio Del Rio, Jose; Sparatore, Fabio; Carotti, Angelo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp) | 1-gen-2018 | Loddo, Roberta; Francesconi, Valeria; Laurini, Erik; Boccardo, Silvia; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina; Tonelli, Michele | |
| Anti-α-glucosidase and antiglycation activities of α-mangostin and new xanthenone derivatives: Enzymatic kinetics and mechanistic insights through in vitro studies | 1-gen-2022 | Djeujo, F. M.; Francesconi, V.; Gonella, M.; Ragazzi, E.; Tonelli, M.; Froldi, G. | |
| Antitarget, Anti-SARS-CoV‑2 Leads, Drugs, and the Drug Discovery−Genetics Alliance Perspective | 1-gen-2023 | Pozzi, Cecilia; Vanet, Anne; Francesconi, Valeria; Tagliazucchi, Lorenzo; Tassone, Giusy; Venturelli, Alberto; Spyrakis, Francesca; Mazzorana, Marco; Paola Costi, Maria; Tonelli, Michele | |
| Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives | 1-gen-2022 | Barbieri, Federica; Bosio, Alessia Graziana; Pattarozzi, Alessandra; Tonelli, Michele; Bajetto, Adriana; Verduci, Ivan; Cianci, Francesca; Cannavale, Gaetano; Palloni, Luca M G; Francesconi, Valeria; Thellung, Stefano; Fiaschi, Pietro; Mazzetti, Samanta; Schenone, Silvia; Balboni, Beatrice; Girotto, Stefania; Malatesta, Paolo; Daga, Antonio; Zona, Gianluigi; Mazzanti, Michele; Florio, Tullio | |
| Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays | 1-gen-2023 | Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele | |
| Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment | 1-gen-2024 | Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia | |
| Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase | 1-gen-2021 | Tassone, G.; Landi, G.; Linciano, P.; Francesconi, V.; Tonelli, M.; Tagliazucchi, L.; Costi, M. P.; Mangani, S.; Pozzi, C. | |
| Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA–PB1 Subunits Interaction | 1-gen-2024 | Giacchello, Ilaria; Cianciusi, Annarita; Bertagnin, Chiara; Bonomini, Anna; Francesconi, Valeria; Mori, Mattia; Carbone, Anna; Musumeci, FRANCESCA MICHELA; Loregian, Arianna; Schenone, Silvia | |
| Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents | 1-gen-2024 | Francesconi, V.; Rizzo, M.; Pozzi, C.; Tagliazucchi, L.; Konchie Simo, C. U.; Saporito, G.; Landi, G.; Mangani, S.; Carbone, A.; Schenone, S.; Santarem, N.; Tavares, J.; Cordeiro-Da-Silva, A.; Costi, M. P.; Tonelli, M. | |
| Journey on naphthoquinone and anthraquinone derivatives: New insights in alzheimer’s disease | 1-gen-2021 | Campora, M.; Francesconi, V.; Schenone, S.; Tasso, B.; Tonelli, M. | |
| Novel 1-amidino-4-phenylpiperazines as potent agonists at human taar1 receptor: Rational design, synthesis, biological evaluation and molecular docking studies | 1-gen-2020 | Francesconi, V.; Cichero, E.; Kanov, E. V.; Laurini, E.; Pricl, S.; Gainetdinov, R. R.; Tonelli, M. | |
| Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents | 1-gen-2021 | Cichero, Elena; Calautti, Alessio; Francesconi, Valeria; Tonelli, Michele; Schenone, Silvia; Fossa, Paola | |
| State-of-the-art Review on the Antiparasitic Activity of Benzimidazole-based Derivatives: Facing Malaria, Leishmaniasis, and Trypanosomiasis | 1-gen-2024 | Francesconi, Valeria; Rizzo, Marco; Schenone, Silvia; Carbone, Anna; Tonelli, Michele | |
| Synthesis and biological evaluation of nitrogen heterocycle systems as potential antiviral agents | 20-mar-2020 | Francesconi, Valeria | |
| Synthesis and biological evaluation of novel (thio)semicarbazone-based benzimidazoles as antiviral agents against human respiratory viruses | 1-gen-2020 | Francesconi, Valeria; Cichero, Elena; Schenone, Silvia; Naesens, Lieve; Tonelli, Michele | |
| Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR) | 1-gen-2018 | Francesconi, Valeria; Luca, Giovannini; Santucci, Matteo; Cichero, Elena; Paola Costi, Maria; Naesens, Lieve; Giordanetto, Fabrizio; Tonelli, Michele | |
| Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease | 1-gen-2023 | Tonelli, Michele; Catto, Marco; Sabaté, Raimon; Francesconi, Valeria; Laurini, Erik; Pricl, Sabrina; Pisani, Leonardo; Valeria Miniero, Daniela; Maria Liuzzi, Grazia; Gatta, Elena; Relini, Annalisa; Gavín, Rosalina; Antonio Del Rio, Jose; Sparatore, Fabio; Carotti, Angelo |