Sfoglia per Autore
Human T cell recognition of cloned HLA class I gene products expressed on DNA transfectants of mouse mastocytoma P815.
1985-01-01 Maryanski, Jl; Moretta, Alessandro; Jordan, B; De Plaen, E; Van Pel, A; Boon, T; Cerottini, Jc
Frequency and surface phenotype of human T lymphocytes producing interleukin 2. Analysis by limiting dilution and cell cloning.
1985-01-01 Moretta, Alessandro
Cyclosporin-A inhibits IL-2 production by all human T-cell clones having this function, independent of the T4/T8 phenotype or the coexpression of cytolytic activity.
1986-01-01 Ferrini, S; Moretta, Alessandro; Biassoni, R; Nicolin, A; Moretta, Lorenzo
Modulation of surface T11 molecules induced by monoclonal antibodies: analysis of the functional relationship between antigen-dependent and antigen-independent pathways of human T cell activation.
1986-01-01 Moretta, Alessandro; Olive, D; Poggi, A; Pantaleo, G; Mawas, C; Moretta, Lorenzo
Signal transducing mechanisms involved in human T cell activation via surface T44 molecules. Comparison with signals transduced via the T cell receptor complex.
1986-01-01 Pantaleo, G; Olive, D; Harris, D; Poggi, A; Moretta, Alessandro; Moretta, Lorenzo
Tp44 molecules involved in antigen-independent T cell activation are expressed on human plasma cells.
1987-01-01 Kozbor, D; Moretta, Alessandro; Messner, Ha; Moretta, Lorenzo; Croce, Cm
Phenotypic and functional characterization of recombinant interleukin 2 (rIL 2)-induced activated killer cells: analysis at the population and clonal levels.
1987-01-01 Ferrini, S; Miescher, S; Zocchi, Mr; von Fliedner, V; Moretta, Alessandro
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function.
1987-01-01 Zocchi, Mr; Bottino, Cristina; Ferrini, S; Moretta, Alessandro; Moretta, Lorenzo
Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery.
1987-01-01 Ferrini, S; Bottino, Cristina; Biassoni, R; Poggi, A; Sekaly, Rp; Moretta, Alessandro; Moretta, Lorenzo
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
1987-01-01 Mingari, MARIA CRISTINA; Ferrini, S; Pende, D; Bottino, Cristina; Prigione, I; Moretta, Alessandro; Moretta, Lorenzo
Selection and characterization of T-cell variants lacking molecules involved in T-cell activation (T3 T-cell receptor, T44, and T11): analysis of the functional relationship among different pathways of activation.
1987-01-01 Moretta, Alessandro; Poggi, A; Olive, D; Bottino, Cristina; Fortis, C; Pantaleo, G; Moretta, Lorenzo
Antibody-induced modulation of the CD3/T cell receptor complex causes T cell refractoriness by inhibiting the early metabolic steps involved in T cell activation.
1987-01-01 Pantaleo, G; Olive, D; Poggi, A; Pozzan, T; Moretta, Alessandro; Moretta, Lorenzo
Surface markers of human lymphokine-activated killer cells and their precursors. Analysis at the population and clonal level.
1987-01-01 Ferrini, S; Moretta, Alessandro; Pantaleo, G; Moretta, Lorenzo
Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product.
1987-01-01 Pantaleo, G; Ferrini, S; Zocchi, Mr; Bottino, Cristina; Biassoni, R; Moretta, Alessandro; Moretta, Lorenzo
Transmembrane signalling via the T11-dependent pathway of human T cell activation. Evidence for the involvement of 1,2-diacylglycerol and inositol phosphates.
1987-01-01 Pantaleo, G; Olive, D; Poggi, A; Kozumbo, Wj; Moretta, Alessandro; Moretta, Lorenzo
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
1987-01-01 Bottino, Cristina; Ferrini, S; Ciccone, E; Prigione, I; Pende, D; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
1987-01-01 Moretta, Alessandro; Pende, D; Bottino, Cristina; Migone, N; Ciccone, Ermanno; Ferrini, S; Mingari, MARIA CRISTINA; Moretta, Lorenzo
CD3+4-8-WT31-(T cell receptor gamma+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2-responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis.
1987-01-01 DE MARIA, Andrea; Malnati, M; Moretta, Alessandro; Pende, D; Bottino, Cristina; Casorati, G; Cottafava, F; Melioli, G; Mingari, MARIA CRISTINA; Migone, N.
CD3+ WT31- peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the alpha/beta heterodimer.
1987-01-01 Poggi, A; Bottino, Cristina; Zocchi, Mr; Pantaleo, G; Ciccone, Ermanno; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
CD3-negative lymphokine-activated cytotoxic cells express the CD3 epsilon gene.
1988-01-01 Biassoni, R; Ferrini, S; Prigione, I; Moretta, Alessandro; Long, Eo
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