Purpose: To investigate the effects of implantation of a phakic iris-fixated intraocular lens (IOL) on aqueous flow in the anterior chamber. Methods: We use a mathematical model to study fluid flow in the anterior chamber in the presence of a IOL. The governing equations are solved numerically using the free software OpenFoam. Results: IOL implantation has very little influence on the pressure in the anterior chamber, unless the IOL is placed very close to the iris. The presence of the IOL significantly modifies the thermal flow induced by temperature differences between the cornea and the posterior region of the chamber. The maximum corneal WSS does not increase for normal IOL placement. Relatively large values of the WSS can be attained on the iris. Conclusions: The numerical simulations suggest that cell detachment from the iris and cornea, which is a known possible complication of IOL implantation, is not induced by large values of the WSS. In the case of correct IOL placement the intraocular pressure (IOP) is almost unaffected.

Fluidodinamica della camera anteriore dell'occhio in presenza di lenti intraoculari

REPETTO, RODOLFO;PRALITS, JAN OSCAR;
2014-01-01

Abstract

Purpose: To investigate the effects of implantation of a phakic iris-fixated intraocular lens (IOL) on aqueous flow in the anterior chamber. Methods: We use a mathematical model to study fluid flow in the anterior chamber in the presence of a IOL. The governing equations are solved numerically using the free software OpenFoam. Results: IOL implantation has very little influence on the pressure in the anterior chamber, unless the IOL is placed very close to the iris. The presence of the IOL significantly modifies the thermal flow induced by temperature differences between the cornea and the posterior region of the chamber. The maximum corneal WSS does not increase for normal IOL placement. Relatively large values of the WSS can be attained on the iris. Conclusions: The numerical simulations suggest that cell detachment from the iris and cornea, which is a known possible complication of IOL implantation, is not induced by large values of the WSS. In the case of correct IOL placement the intraocular pressure (IOP) is almost unaffected.
2014
9788890456183
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11567/768203
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