threo-α-Dibenzylamino-beta-hydroxyesters (2) have been synthesised with high diastereoselectivity through the NaBH4 reduction of α-dibenzylamino-β-oxoesters (4) and then tranformed into threo-α-amino-β-hydroxyacids.
Diastereoselective Synthesis of alpha-Amino-beta-hydroxyacids
GUANTI, GIUSEPPE;BANFI, LUCA;NARISANO, ENRICA;
1984-01-01
Abstract
threo-α-Dibenzylamino-beta-hydroxyesters (2) have been synthesised with high diastereoselectivity through the NaBH4 reduction of α-dibenzylamino-β-oxoesters (4) and then tranformed into threo-α-amino-β-hydroxyacids.
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