Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects. © 2014 Elsevier Inc. All rights reserved.
Juvenile Idiopathic Arthritis
Malattia C.;Martini A.
2013-01-01
Abstract
Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects. © 2014 Elsevier Inc. All rights reserved.
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