To the Editor: In a randomized, controlled trial, Merlano et al. (Oct. 15 issue)1 present data showing improved overall survival and progression-free survival among patients with advanced head and neck cancer treated by alternating radiotherapy and chemotherapy as compared with radiotherapy alone. Before this finding can be regarded as proof that combined treatment is superior to radiotherapy alone, an explanation of why the patients treated only with radiotherapy fared so badly is essential. Published data suggest that radiotherapy is capable of giving much better results, even in patients with advanced lesions. Merlano et al. do not directly compare data on… © 1993, Massachusetts Medical Society. All rights reserved.
Radiotherapy plus Chemotherapy for Head and Neck Cancer
Corvo R.
1993-01-01
Abstract
To the Editor: In a randomized, controlled trial, Merlano et al. (Oct. 15 issue)1 present data showing improved overall survival and progression-free survival among patients with advanced head and neck cancer treated by alternating radiotherapy and chemotherapy as compared with radiotherapy alone. Before this finding can be regarded as proof that combined treatment is superior to radiotherapy alone, an explanation of why the patients treated only with radiotherapy fared so badly is essential. Published data suggest that radiotherapy is capable of giving much better results, even in patients with advanced lesions. Merlano et al. do not directly compare data on… © 1993, Massachusetts Medical Society. All rights reserved.
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