IRIS
FEDELE, ERNESTO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 16.438
Totale 16.438
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 16.438
Totale 16.438
Salva come PNG Salva come JPEG
Città #
Genova 12.140
Rapallo 1.813
Genoa 1.399
Vado Ligure 1.053
Bordighera 33
Totale 16.438
Salva come PNG Salva come JPEG
Nome #
Presynaptic GLP-1 receptors enhance the depolarization-evoked release of Glutamate and GABA in the mouse cortex and hippocampus 162
Phosphodiesterase-4D: an enzyme to remember 161
Glycine modulates 3H-noradrenaline release in rat hippocampus through a strychnine-sensitive receptor 159
Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease. 158
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment 154
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors 151
Antagonizing α7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition 148
[3H]Glycine uptake in rat hippocampus: kinetic analysis and autoradiographic localization. 146
Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism 144
D-SERINE MODULATES THE NMDA RECEPTOR/NITRIC OXIDE/cGMP PATHWAY IN THE RAT CEREBELLUM DURING IN VIVO MICRODIALYSIS 144
Amyloid β: Walking on the dark side of the moon 142
Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites 140
A novel PDE4D inhibitor increases amyloid-beta deposition in neuronal cultured cells and improves memory in rats 139
Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis. 139
The amyloid cascade hypothesis in Alzheimer’s disease: it’s time to change our mind 139
l-Aspartate as an amino acid neurotransmitter: mechanisms of the depolarization-induced release from cerebrocortical synaptosomes. 138
Presynaptic nicotinic receptors evoke endogenous glutamate and aspartate release from hippocampal synaptosomes by way of distinct coupling mechanisms 138
INTRACEREBRAL ADMINISTRATION OF L-KYNURENINE DECREASES N-METHYL-D-ASPARTATE RECEPTOR-MEDIATED PRODUCTION OF cGMP IN THE CEREBELLUM AND HIPPOCAMPUS OF UNANAESTHETIZED RATS SUBJECTED TO TRANSCEREBRAL MICRODIALYSIS 137
Reduced GABA Content in the Motor Thalamus during Effective Deep Brain Stimulation of the Subthalamic Nucleus. 135
Alterations of glutamate release in the spinal cord of mice with experimental autoimmune encephalomyelitis 135
Acetylcholine release from rat hippocampal slices is modulated by 5-hydroxytryptamine. 134
Release-regulating dopamine autoreceptors in human cerebral cortex. 134
Age-related decrease of the NMDA receptor-mediated noradrenaline release in rat hippocampus and partial restoration by D-cycloserine 134
Amyloid Beta and the Brain: Where Are We Now? 132
Release-regulating GABAB autoreceptors in rat cerebral cortex slices 131
GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. 131
Cyclooxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus. 130
Delayed administration may improve entacapone effects in parkinsonian patients non-responding to the drug. 128
Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) Related Phosphodiesterase 4D (PDE4D) Inhibitors. 127
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum. 125
DESENSITIZATION OF AMPA RECEPTORS AND AMPA-NMDA RECEPTOR INTERACTION: AN IN VIVO CYCLIC GMP MICRODIALYSIS STUDY IN RAT CEREBELLUM 123
In vivo studies of glutamatergic receptors and NO pathways in brain 122
Autoradiographical evaluation of [3H]glycine uptake in rat forebrain: cellular localization in the hippocampus. 120
A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: role of amyloid beta 120
PDE4D inhibitors: a potential strategy for the treatment of memory impairment? 120
Cyclic adenosine monophosphate as an endogenous modulator of the amyloid-β precursor protein metabolism 119
Glucagon-Like Peptide 1, Neuroprotection and Neurodegenerative Disorders 119
Microdialysis in Parkinsonian patient basal ganglia: acute apomorphine-induced clinical and electrophysiological effects not paralleled by changes in the release of neuroactive amino acids 118
Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition 118
Amyloid-beta peptide is needed for cGMP-induced long-term potentiation and memory 118
In vivo studies of glutamatergic receptors and NO pathways in brain 117
Dopamine release and dopaminergic inhibition of acetylcholine release in rat striatal slices after nigro-striatal hemitransection and parenteral ganglioside administration 115
Serotonin receptors regulating transmitter release 115
New compounds having a selective PDE4D inhibiting activity 114
ACTIVATION OF BRAIN NITRIC OXIDE SYNTHASE IN DEPOLARIZED HUMAN TEMPORAL CORTEX SLICES: DIFFERENTIAL ROLE OF VOLTAGE-SENSITIVE CALCIUM CHANNELS 113
Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor 112
A physiological role for amyloid beta in the cyclic AMP-stimulated long term potentiation. 112
IN VIVO MICRODIALYSIS STUDY OF A SPECIFIC INHIBITOR OF SOLUBLE GUANYLYL CYCLASE ON THE GLUTAMATE RECEPTOR/NITRIC OXIDE/CYCLIC GMP PATHWAY 112
In vivo effects of phosphodiesterase inhibition on basal cGMP levels in the pre-frontal cortex, hippocampus and cerebellum of freely moving rats. 111
The clinical efficacy of L-DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus. 111
Presynaptic nicotinic α7 and non-α7 receptors stimulate endogenous GABA release from rat hippocampal synaptosomes through two mechanisms of action. 111
Functional damage of dopamine nerve terminals following intrastriatal kainic acid injection 111
THE GLUTAMATE RECEPTOR/NO/CYCLIC GMP PATHWAY IN THE HIPPOCAMPUS OF FREELY-MOVING RATS: MODULATION BY CYCLOTHIAZIDE, INTERACTION WITH GABA AND THE BEHAVIOURAL CONSEQUENCES 110
In vivo investigation of the NMDA/NOS/CGMP pathway during aging in the hippocampus and cerebellum of freely-moving rats 110
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex 110
Effects of phosphodiesterase inhibition on cortical spreading depression and associated changes in extracellular cyclic GMP 110
Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by ‘pathologically’ elevated extraterminal K+ concentrations 109
TRANSMITTER RELEASE ASSOCIATED WITH LONG-TERM SYNAPTIC DEPRESSION IN RAT CORTICOSTRIATAL SLICES 109
Subthalamic stimulation activates internal pallidus: evidence from cGMP microdialysis in PD patients 108
Glycine stimulates [3H]noradrenaline release by activating a strychnine-sensitive receptor present in rat hippocampus. 107
Altered Fronto-Striatal Functions in the Gdi1-null Mouse Model of X-linked Intellectual Disability 107
Homovanillic acid in CSF of mild stage Parkinson’s disease patients correlates with motor impairment 107
Microdialysis study in vivo of the nitric oxide/cGMP pathway in the hippocampus and cerebellum of adult and aged rats 106
Correlation between changes in CSF dopamine turnover and development of dyskinesia in Parkinson’s disease. 106
Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression 106
γ-Aminobutyric acidB receptors mediate inhibition of somatostatin release from cerebrocortex nerve terminals. 105
Native human neocortex release-regulating dopamine D2 type autoreceptors are dopamine D2 subtype 105
Cholinergic modulation of 3H-dopamine release from dendrosomes of rat substantia nigra 105
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum. 102
Clinical and electrophysiological effects of apomorphine in Parkinson's disease are not paralleled by aminoacid release changes: a microdialysis study 102
Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells 102
cAMP, cGMP and Amyloid Beta: three ideal partners for memory formation 102
In vivo activation of N-methyl-D-aspartate receptors in the rat hippocampus increases prostaglandin E2 extracellular levels and triggers lipid peroxidation through cyclooxygenase-mediated mechanisms 101
Deep brain stimulation in Parkinson’s disease patients: biochemical evidence 101
γ-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex. 101
GABAA, but not NMDA, receptors modulate in vivo NO-mediated cGMP synthesis in the rat cerebral cortex 99
Temporal administration of entacapone with slow release l-dopa: pharmacokinetic profile and clinical outcome. 96
The pharmacological blockade of medial forebrain bundle induces an acute pathological synchronization of the cortico-subthalamic nucleus-globus pallidus pathway 96
Biochemical and electrophysiological changes of substantia nigra pars reticolata driver by subthalamic stimulation in patients with Parkinson’s disease 96
null 96
The NOS/sGC pathway in the rat central nervous system: a microdialysis overview 95
Native human release-regulating dopamine autoreceptors in the cerebral cortex belong to the D2 type D2 subtype 95
Reduced L-DOPA absorption and increased clinical fluctuation in Helicobacter Pylori-infected Parkinson's disease patients 93
Stimulation of the amyloid-β precursor protein metabolism by cAMP 92
Activation of presynaptic Neuropeptide S receptors inhibits the release of 5-HT and glycine in mouse frontal/prefrontal cortex and amygdala 92
cAMP-induced Aβ production and its role in the expression of LTP. 92
Age-related decrease of the NMDA receptor-mediated noradrenaline release in rat hippocampus and partial restoration by D-cycloserine 92
Microdialysis in parkinsonian patient basal ganglia: apomorphine effect without changes in the release of neuroactive amino acids 91
Long term effects of helicobacter pylory eradication on l-dopa absorption in Parkinson’s disease patients 91
Isolation of hydroxyoctaprenyl-1’,4’-hydroquinone, a new octaprenylhydroquinone from the marine sponge Sarcotragus spinosulus and evaluation of its pharmacological activity on acetylcholine and glutamate release in the rat Central Nervous System. 91
Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D 90
Subtype of 5-HT1 receptor regulating [3H]acetylcholine release from superfused hippocampal slices and synaptosomes 89
Helicobacter Pylori-induced reduction of l-dopa acute absorption in Parkinson’s disease patients 88
Effects of dopamine receptor agonists on the efflux of excitatory and inhibitory amino acids in Parkinson's disease patients: A microdialysis approach 88
Studies in vivo of the nitric oxide/cyclic GMP pathway in the brain 88
null 88
Gebr-7b, a novel selective PDE4D inhibitor, increases beta amyloid secretion in neuronal cultured cells and improves cognitive function in rodents 87
A novel cAMP/PKA/APP/Abeta pathway modulates hippocampal LTP 86
NICOTINE ADMINISTRATION STIMULATES THE IN VIVO N-METHYL-D-ASPARTATE RECEPTOR/NITRIC OXIDE/CYCLIC GMP PATHWAY IN RAT HIPPOCAMPUS THROUGH GLUTAMATE RELEASE 82
Glutamic acid and GABA modulate each other's release through heterocarriers sited on the axon terminal of rat brain 81
Totale 11.471
Salva come PNG Salva come JPEG
Categoria #
all - tutte 49.721
article - articoli 36.277
book - libri 0
conference - conferenze 11.686
curatela - curatele 0
other - altro 0
patent - brevetti 222
selected - selezionate 0
volume - volumi 1.536
Totale 99.442
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.490 0 0 0 0 317 385 758 234 308 794 573 121
2020/20211.165 58 89 64 72 52 179 125 92 94 143 104 93
2021/20222.128 49 212 137 224 55 134 124 541 121 183 99 249
2022/20232.179 218 154 46 215 346 408 15 153 417 11 162 34
2023/20241.056 52 177 24 160 86 181 60 64 39 24 60 129
2024/20251.093 70 266 125 244 388 0 0 0 0 0 0 0
Totale 16.900