Sfoglia per Autore
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation
2007-01-01 THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Corsaro, Alessandro; Pellistri, Francesca; Venezia, Valentina; Russo, C; Aceto, A; Robello, Mauro; Florio, Tullio
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion
2008-01-01 THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Gatta, Elena; Robello, Mauro; Florio, Tullio
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231
2009-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Chiovitti, K; Villa, Valentina; Simi, A; Raggi, F; Paludi, D; Russo, C; Aceto, A; Florio, Tullio
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability
2010-01-01 Thellung, S.; Corsaro, A.; Villa, V.; Florio, Tullio
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation
2010-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T.; Scotti, L.; Chiovitti, K.; Villa, Valentina; D’Arrigo, C.; Aceto, A.; Florio, Tullio
The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization
2010-01-01 Corsaro, Alessandro; Anselmi, C; Polano, M; Aceto, A; Florio, Tullio; DE NOBILI, M.
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation.
2010-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Florio, Tullio
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231)
2011-01-01 Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Simi, A.; Nizzari, Mario; Tonelli, Michele; Boido, Vito; Aceto, A.; Florio, Tullio
New therapeutic strategies for Alzheimer’s disease by determination of structure and toxicity of oligomeric beta-amyloids aggregation states
2011-01-01 D’Arrigo, C.; Galante, D.; Florio, Tullio; Corsaro, Alessandro; Vassalli, M.; Sbrana, F.; Perico, A.
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development
2011-01-01 Barbieri, Federica; Bajetto, Adriana; Pattarozzi, Alessandra; Gatti, Monica; Wurth, Roberto; Porcile, C; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Florio, Tullio
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity
2011-01-01 Villa, Valentina; Tonelli, Michele; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Tasso, Bruno; Novelli, Federica; Canu, Caterina; Pino, Albiana; Chiovitti, K.; Paludi, D.; Russo, C.; Sparatore, A.; Aceto, A.; Boido, Vito; Sparatore, Fabio; Florio, Tullio
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein
2011-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T; Scotti, L; Chiovitti, K.; Villa, Valentina; Darrigo, C; Aceto, A; Florio, Tullio
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction
2011-01-01 THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Simi, A; Vella, SERENA LUISA; Pagano, Aldo; Florio, Tullio
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids
2012-01-01 Galante, Denise; Corsaro, Alessandro; Florio, Tullio; Vella, SERENA LUISA; Pagano, Aldo; Sbrana, F.; Vassalli, M.; Perico, A.; D’Arrigo, C.
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231
2012-01-01 Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Tonelli, Michele; Tasso, Bruno; Sparatore, Fabio; Silvia, Leone; Fucile, Carmen; Florio, Tullio
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure
2012-01-01 Sorrentino, S.; Bucciarelli, T.; Corsaro, Alessandro; Tosatto, A.; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Schininà, M. E.; Maras, B.; Galeno, R.; Scotti, L.; Creati, F.; Marrone, A.; Re, N.; Aceto, A.; Florio, Tullio; Mazzanti, M.
Role of prion protein aggregation in neurotoxicity
2012-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Florio, Tullio
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity
2012-01-01 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Aceto, A.; Florio, Tullio
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling
2012-01-01 Nizzari, Mario; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Pagano, Aldo; Porcile, C.; Russo, C.; Florio, Tullio
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity
2012-01-01 Corsaro, A.; Thellung, S.; Villa, V.; Nizzari, M.; Aceto, A.; Florio, T.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation | 1-gen-2007 | THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Corsaro, Alessandro; Pellistri, Francesca; Venezia, Valentina; Russo, C; Aceto, A; Robello, Mauro; Florio, Tullio | |
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion | 1-gen-2008 | THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Gatta, Elena; Robello, Mauro; Florio, Tullio | |
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 | 1-gen-2009 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Chiovitti, K; Villa, Valentina; Simi, A; Raggi, F; Paludi, D; Russo, C; Aceto, A; Florio, Tullio | |
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability | 1-gen-2010 | Thellung, S.; Corsaro, A.; Villa, V.; Florio, Tullio | |
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation | 1-gen-2010 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T.; Scotti, L.; Chiovitti, K.; Villa, Valentina; D’Arrigo, C.; Aceto, A.; Florio, Tullio | |
The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization | 1-gen-2010 | Corsaro, Alessandro; Anselmi, C; Polano, M; Aceto, A; Florio, Tullio; DE NOBILI, M. | |
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. | 1-gen-2010 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Florio, Tullio | |
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) | 1-gen-2011 | Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Simi, A.; Nizzari, Mario; Tonelli, Michele; Boido, Vito; Aceto, A.; Florio, Tullio | |
New therapeutic strategies for Alzheimer’s disease by determination of structure and toxicity of oligomeric beta-amyloids aggregation states | 1-gen-2011 | D’Arrigo, C.; Galante, D.; Florio, Tullio; Corsaro, Alessandro; Vassalli, M.; Sbrana, F.; Perico, A. | |
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development | 1-gen-2011 | Barbieri, Federica; Bajetto, Adriana; Pattarozzi, Alessandra; Gatti, Monica; Wurth, Roberto; Porcile, C; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Florio, Tullio | |
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity | 1-gen-2011 | Villa, Valentina; Tonelli, Michele; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Tasso, Bruno; Novelli, Federica; Canu, Caterina; Pino, Albiana; Chiovitti, K.; Paludi, D.; Russo, C.; Sparatore, A.; Aceto, A.; Boido, Vito; Sparatore, Fabio; Florio, Tullio | |
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein | 1-gen-2011 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T; Scotti, L; Chiovitti, K.; Villa, Valentina; Darrigo, C; Aceto, A; Florio, Tullio | |
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction | 1-gen-2011 | THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Simi, A; Vella, SERENA LUISA; Pagano, Aldo; Florio, Tullio | |
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids | 1-gen-2012 | Galante, Denise; Corsaro, Alessandro; Florio, Tullio; Vella, SERENA LUISA; Pagano, Aldo; Sbrana, F.; Vassalli, M.; Perico, A.; D’Arrigo, C. | |
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 | 1-gen-2012 | Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Tonelli, Michele; Tasso, Bruno; Sparatore, Fabio; Silvia, Leone; Fucile, Carmen; Florio, Tullio | |
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure | 1-gen-2012 | Sorrentino, S.; Bucciarelli, T.; Corsaro, Alessandro; Tosatto, A.; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Schininà, M. E.; Maras, B.; Galeno, R.; Scotti, L.; Creati, F.; Marrone, A.; Re, N.; Aceto, A.; Florio, Tullio; Mazzanti, M. | |
Role of prion protein aggregation in neurotoxicity | 1-gen-2012 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Florio, Tullio | |
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity | 1-gen-2012 | Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Aceto, A.; Florio, Tullio | |
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling | 1-gen-2012 | Nizzari, Mario; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Pagano, Aldo; Porcile, C.; Russo, C.; Florio, Tullio | |
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity | 1-gen-2012 | Corsaro, A.; Thellung, S.; Villa, V.; Nizzari, M.; Aceto, A.; Florio, T. |
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