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Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability 1-gen-2010 Thellung, S.; Corsaro, A.; Villa, V.; Florio, Tullio
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation 1-gen-2010 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T.; Scotti, L.; Chiovitti, K.; Villa, Valentina; D’Arrigo, C.; Aceto, A.; Florio, Tullio
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. 1-gen-2010 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Florio, Tullio
The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization 1-gen-2010 Corsaro, Alessandro; Anselmi, C; Polano, M; Aceto, A; Florio, Tullio; DE NOBILI, M.
New therapeutic strategies for Alzheimer’s disease by determination of structure and toxicity of oligomeric beta-amyloids aggregation states 1-gen-2011 D’Arrigo, C.; Galante, D.; Florio, Tullio; Corsaro, Alessandro; Vassalli, M.; Sbrana, F.; Perico, A.
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity 1-gen-2011 Villa, Valentina; Tonelli, Michele; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Tasso, Bruno; Novelli, Federica; Canu, Caterina; Pino, Albiana; Chiovitti, K.; Paludi, D.; Russo, C.; Sparatore, A.; Aceto, A.; Boido, Vito; Sparatore, Fabio; Florio, Tullio
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 1-gen-2011 Barbieri, Federica; Bajetto, Adriana; Pattarozzi, Alessandra; Gatti, Monica; Wurth, Roberto; Porcile, C; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Florio, Tullio
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 1-gen-2011 THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Simi, A; Vella, SERENA LUISA; Pagano, Aldo; Florio, Tullio
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) 1-gen-2011 Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Simi, A.; Nizzari, Mario; Tonelli, Michele; Boido, Vito; Aceto, A.; Florio, Tullio
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein 1-gen-2011 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Bucciarelli, T; Scotti, L; Chiovitti, K.; Villa, Valentina; Darrigo, C; Aceto, A; Florio, Tullio
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 1-gen-2012 Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Tonelli, Michele; Tasso, Bruno; Sparatore, Fabio; Silvia, Leone; Fucile, Carmen; Florio, Tullio
Role of prion protein aggregation in neurotoxicity 1-gen-2012 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Florio, Tullio
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 1-gen-2012 Sorrentino, S.; Bucciarelli, T.; Corsaro, Alessandro; Tosatto, A.; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Schininà, M. E.; Maras, B.; Galeno, R.; Scotti, L.; Creati, F.; Marrone, A.; Re, N.; Aceto, A.; Florio, Tullio; Mazzanti, M.
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling 1-gen-2012 Nizzari, Mario; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Pagano, Aldo; Porcile, C.; Russo, C.; Florio, Tullio
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity 1-gen-2012 Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Villa, Valentina; Nizzari, Mario; Aceto, A.; Florio, Tullio
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids 1-gen-2012 Galante, Denise; Corsaro, Alessandro; Florio, Tullio; Vella, SERENA LUISA; Pagano, Aldo; Sbrana, F.; Vassalli, M.; Perico, A.; D’Arrigo, C.
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 1-gen-2013 Barbieri, Federica; Bajetto, Adriana; Pattarozzi, Alessandra; Gatti, Monica; Wurth, Roberto; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Florio, Tullio
Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt 1-gen-2013 Wurth, Roberto; Pattarozzi, Alessandra; Gatti, Monica; Bajetto, Adriana; Corsaro, Alessandro; Parodi, A; Sirito, R; Massollo, Michela; Marini, C; Zona, Gianluigi; Fenoglio, Daniela; Sambuceti, Gianmario; Filaci, Gilberto; Daga, A; Barbieri, Federica; Florio, Tullio
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 1-gen-2013 Thellung, Stefano; Gatta, Elena; Pellistri, Francesca; Corsaro, Alessandro; Villa, Valentina; Vassalli, M; Robello, Mauro; Florio, Tullio
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 1-gen-2014 Corsaro, A; Raccosta, S; De Stefano, S; Thellung, S; Villa, V; Manno, M; Martorana, V; Vassalli, M; Florio, T
Mostrati risultati da 41 a 60 di 76
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