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Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 1-gen-2009 Bruzzone, Santina; Fruscione, Floriana; Morando, Sara; Ferrando, Tiziana; Poggi, A.; Garuti, Anna; D'Urso, A.; Selmo, M.; Benvenuto, Federica; Cea, Michele; Zoppoli, Gabriele; Moran, Eva; Soncini, Debora; Ballestrero, Alberto; Sordat, B.; Patrone, Franco; Mostoslavsky, R.; Uccelli, Antonio; Nencioni, Alessio
Potent Synergistic Activity of the NAD plus Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia. 1-gen-2009 Zoppoli, Gabriele; Cea, Michele; Fruscione, Floriana; Bruzzone, Santina; Soncini, Debora; Bedognetti, D.; Moran, Eva; Balleari, E.; Bruzzone, A.; Garuti, Anna; Cirmena, Gabriella; Rocco, Ilaria; Gobbi, Marco; Ghio, Riccardo; Pommier, Y.; Carella, A. M.; Ballestrero, Alberto; Parodi, Silvio; Patrone, Franco; Nencioni, Alessio
Ras-induced resistance to lapatinib is overcome by MEK inhibition 1-gen-2010 Zoppoli, Gabriele; Moran, Eva; Soncini, Debora; Cea, Michele; Garuti, Anna; Rocco, Ilaria; Cirmena, Gabriella; Grillo, V; Bagnasco, Luca; Icardi, Giancarlo; Ansaldi, Filippo; Parodi, Silvio; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 1-gen-2010 Castagnino, Nicoletta; Tortolina, Lorenzo; Balbi, Alessandro; Pesenti, R; Montagna, R; Ballestrero, Alberto; Soncini, Debora; Moran, E; Nencioni, Alessio; Parodi, Silvio
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 1-gen-2010 Cea, Michele; Cagnetta, Antonia; Garuti, Anna; Cirmena, Gabriella; Rocco, Ilaria; Palermo, Claudia; Soncini, Debora; Caffa, Irene; Zoppoli, Gabriele; Pierri, Ivana; Gobbi, Marco; Ballestrero, Alberto; Nencioni, Alessio; Patrone, Franco
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 1-gen-2010 Zoppoli, Gabriele; Cea, Michele; Soncini, Debora; Fruscione, Floriana; J., Rudner; Moran, Eva; Caffa, Irene; Bedognetti, Davide; Motta, Giovanni; Ghio, Riccardo; Ferrando, Fabio; Ballestrero, Alberto; Parodi, Silvio; C., Belka; Patrone, Franco; Bruzzone, Santina; Nencioni, Alessio
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 1-gen-2010 Nencioni, Alessio; Cea, Michele; Garuti, Anna; Passalacqua, Mario; Raffaghello, L.; Soncini, Debora; Moran, Eva; Zoppoli, Gabriele; Pistoia, V.; Patrone, Franco; Ballestrero, Alberto
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 1-gen-2011 Cea, Michele; Soncini, Debora; Fruscione, Floriana; Raffaghello, L; Garuti, Anna; Emionite, Laura; Moran, Eva; Magnone, Mirko; Zoppoli, Gabriele; Reverberi, D; Caffa, Irene; Salis, Annalisa; Cagnetta, Antonia; Bergamaschi, M; Casciaro, S; Pierri, Ivana; Damonte, Gianluca; Ansaldi, Filippo; Gobbi, Marco; Pistoia, Vito; Ballestrero, Alberto; Patrone, Franco; Bruzzone, Santina; Nencioni, Alessio
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 1-gen-2011 Caffa, Irene; Soncini, Debora; Zoppoli, Gabriele; Moran, Eva; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 1-gen-2011 Soncini, Debora; Caffa, Irene; Zoppoli, Gabriele; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 1-gen-2011 Cea, M; Vigliarolo, T; Soncini, D; Fruscione, F; Garuti, A; Moran, E; Zoppoli, G; Caffa, I; Cagnetta, A; Casciaro, S; Pierri, I; Gobbi, M; Pistoia, V; Ballestrero, A; Patrone, F; De Flora, A; Bruzzone, S; Nencioni, A.
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 1-gen-2011 Soncini, Debora; Caffa, Irene; Zoppoli, Gabriele; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 1-gen-2011 Caffa, Irene; Soncini, Debora; Zoppoli, Gabriele; Moran, Eva; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. 1-gen-2012 Soncini, Debora; Caffa, Irene; Patrone, Franco; Ballestrero, Alberto; Nencioni, Alessio
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses 1-gen-2012 Bauer, Inga; Grozio, Alessia; Lasiglie', Denise; Basile, Giovanna; Sturla, Laura; Magnone, Mirko; Sociali, Giovanna; Soncini, Debora; Caffa, Irene; Poggi, A; Zoppoli, Gabriele; Cea, Michele; Feldmann, G; Mostoslavsky, R; Ballestrero, Alberto; Patrone, Franco; Bruzzone, Santina; Nencioni, Alessio
Synergistic Interaction Between P-glycoprotein Inhibitors and APO866 in Primary Leukemic Cells 1-gen-2012 Soncini, Debora; Bruzzone, Santina; Cagnetta, Antonia; Caffa, Irene; Ballestrero, Alberto; Patrone, Franco; Cea, Michele; Nencioni, Alessio
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 1-gen-2012 Bauer, Inga; Grozio, Alessia; Lasiglie', Denise; Basile, Giovanna; Sturla, Laura; Magnone, Mirko; Sociali, Giovanna; Soncini, Debora; Caffa, Irene; Poggi, A; Zoppoli, Gabriele; Cea, Michele; Feldmann, G; Mostoslavsky, R; Ballestrero, Alberto; Patrone, Franco; Bruzzone, Santina; Nencioni, Alessio
Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. 1-gen-2013 Braunersreuther, V; Montecucco, Fabrizio; Pelli, G; Galan, K; Proudfoot, Ae; Belin, A; Vuilleumier, N; Burger, F; Lenglet, S; Caffa, Irene; Soncini, Debora; Nencioni, Alessio; Vallée, Jp; Mach, F.
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 1-gen-2013 Grozio, Alessia; Sociali, Giovanna; Sturla, Laura; Caffa, Irene; Soncini, Debora; Salis, Annalisa; Raffaelli, N; DE FLORA, Antonio; Nencioni, Alessio; Bruzzone, Santina
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 1-gen-2013 Montecucco, Fabrizio; Cea, Michele; Bauer, I; Soncini, Debora; Caffa, Irene; Lasigliè, D; Nahimana, A; Uccelli, Antonio; Bruzzone, Santina; Nencioni, Alessio
Mostrati risultati da 1 a 20 di 41
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