Sfoglia per Autore
Heterogeneity of B cell growth factor (BCGF)-producing T cells in humans. Clonal analysis of BCGF-producing cells within T4+ and T8+ subsets and evidence for the involvement of different growth factors in different BCGF assays.
1986-01-01 Mingari, MARIA CRISTINA; Gerosa, F; Maggi, E; Cozzani, R; Pende, D; Bottino, Cristina; Poggi, A; Romagnani, S; Moretta, Lorenzo
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function.
1987-01-01 Zocchi, Mr; Bottino, Cristina; Ferrini, S; Moretta, Alessandro; Moretta, Lorenzo
Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery.
1987-01-01 Ferrini, S; Bottino, Cristina; Biassoni, R; Poggi, A; Sekaly, Rp; Moretta, Alessandro; Moretta, Lorenzo
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
1987-01-01 Mingari, MARIA CRISTINA; Ferrini, S; Pende, D; Bottino, Cristina; Prigione, I; Moretta, Alessandro; Moretta, Lorenzo
Selection and characterization of T-cell variants lacking molecules involved in T-cell activation (T3 T-cell receptor, T44, and T11): analysis of the functional relationship among different pathways of activation.
1987-01-01 Moretta, Alessandro; Poggi, A; Olive, D; Bottino, Cristina; Fortis, C; Pantaleo, G; Moretta, Lorenzo
Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product.
1987-01-01 Pantaleo, G; Ferrini, S; Zocchi, Mr; Bottino, Cristina; Biassoni, R; Moretta, Alessandro; Moretta, Lorenzo
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
1987-01-01 Bottino, Cristina; Ferrini, S; Ciccone, E; Prigione, I; Pende, D; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
1987-01-01 Moretta, Alessandro; Pende, D; Bottino, Cristina; Migone, N; Ciccone, Ermanno; Ferrini, S; Mingari, MARIA CRISTINA; Moretta, Lorenzo
CD3+4-8-WT31-(T cell receptor gamma+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2-responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis.
1987-01-01 DE MARIA, Andrea; Malnati, M; Moretta, Alessandro; Pende, D; Bottino, Cristina; Casorati, G; Cottafava, F; Melioli, G; Mingari, MARIA CRISTINA; Migone, N.
CD3+ WT31- peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the alpha/beta heterodimer.
1987-01-01 Poggi, A; Bottino, Cristina; Zocchi, Mr; Pantaleo, G; Ciccone, Ermanno; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.
1988-01-01 Pantaleo, G; Zocchi, Mr; Ferrini, S; Poggi, A; Tambussi, G; Bottino, Cristina; Moretta, Alessandro; Moretta, Lorenzo
Different types of effector cells involved in non-mhc-restricted cytolytic activity.
1988-01-01 Moretta, Alessandro; Ferrini, S; Pantaleo, G; Bottino, Cristina; Tambussi, G; Mingari, MARIA CRISTINA
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.
1988-01-01 Ciccone, Ermanno; Viale, O; Bottino, Cristina; Pende, D; Migone, N; Casorati, G; Tambussi, G; Moretta, Alessandro; Moretta, Lorenzo
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain.
1988-01-01 Moretta, Alessandro; Bottino, Cristina; Ciccone, Ermanno; Tambussi, G; Mingari, MARIA CRISTINA; Ferrini, S; Casorati, G; Varese, P; Viale, O; Migone, N; Moretta, Lorenzo
Clonal analysis of CD4-CD8- human thymocytes expressing a T cell receptor gamma/delta chain. Direct evidence for the de novo expression of CD8 surface antigen and of cytolytic activity against tumor targets.
1988-01-01 Mingari, MARIA CRISTINA; Varese, P; Bottino, Cristina; Melioli, G; Moretta, Alessandro; Moretta, Lorenzo
Interleukin-2-induced proliferation of CD4-CD8- human thymocytes. In vitro expression of CD3 and CD8 antigens and cytolytic activity.
1988-01-01 Mingari, MARIA CRISTINA; Varese, P; Bottino, Cristina; Merli, A; Moretta, Lorenzo
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.
1988-01-01 Bottino, Cristina; Tambussi, G; Ferrini, S; Ciccone, Ermanno; Varese, P; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).
1988-01-01 Ciccone, Ermanno; Ferrini, S; Bottino, Cristina; Viale, O; Prigione, I; Pantaleo, G; Tambussi, G; Moretta, Alessandro; Moretta, Lorenzo
Surface molecules involved in the activation and regulation of T or natural killer lymphocytes in humans.
1989-01-01 Moretta, Alessandro; Ciccone, Ermanno; Pantaleo, G; Tambussi, G; Bottino, Cristina; Melioli, G; Mingari, MARIA CRISTINA; Moretta, Lorenzo
Human thymocytes expressing gamma/delta T-cell receptors.
1989-01-01 Mingari, MARIA CRISTINA; Varese, P; Bottino, Cristina; Tambussi, G; Moretta, Lorenzo
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